Evidence map›Paper›PMID 40362388›Full record

ArticleInternational journal of molecular sciences2025

A Comprehensive Analysis of Chemical Composition and Anti-Inflammatory Effects of Cassava Leaf Extracts in Two Varieties in

Jie Cai, Wenli Zhu, Jingjing Xue, Yanqing Ma, Kaimian Li, Lanyue Zhang, Oluwaseun Olayemi Aluko, Songbi Chen, Xiuqin Luo, Feifei An

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Investigating the Anti-inflammatory Mechanism ofIranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jie CaiTropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Science/Key Laboratory of Agriculture for Germplasm Resources Conservation and Utilization of Cassava, Haikou 571101, China.ORCID 0000-0003-4121-4542
Wenli ZhuTropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Science/Key Laboratory of Agriculture for Germplasm Resources Conservation and Utilization of Cassava, Haikou 571101, China.
Jingjing XueTropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Science/Key Laboratory of Agriculture for Germplasm Resources Conservation and Utilization of Cassava, Haikou 571101, China.
Yanqing MaSchool of Biomedical and Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of Plant Resources Biorefinery, Guangdong University of Technology, Guangzhou 510006, China.
Kaimian LiTropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Science/Key Laboratory of Agriculture for Germplasm Resources Conservation and Utilization of Cassava, Haikou 571101, China.
Lanyue ZhangSchool of Biomedical and Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of Plant Resources Biorefinery, Guangdong University of Technology, Guangzhou 510006, China.
Oluwaseun Olayemi AlukoTropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Science/Key Laboratory of Agriculture for Germplasm Resources Conservation and Utilization of Cassava, Haikou 571101, China.ORCID 0000-0001-9532-4419
Songbi ChenTropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Science/Key Laboratory of Agriculture for Germplasm Resources Conservation and Utilization of Cassava, Haikou 571101, China.
Xiuqin LuoTropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Science/Key Laboratory of Agriculture for Germplasm Resources Conservation and Utilization of Cassava, Haikou 571101, China.
Feifei AnTropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Science/Key Laboratory of Agriculture for Germplasm Resources Conservation and Utilization of Cassava, Haikou 571101, China.

Funding

National Key Research and Development Program of China 2023YFD1200200
6 · The paper itself

Abstract

Cassava is a tropical tuberous root crop, feeding over a billion people globally. However, research on the chemical composition and bioactive effects of cassava leaves remains scarce. Two specific varieties of South China No. 9 (green leaves (G.L.)) and South China No. 20 (purple leaves (P.L.)) were investigated in this study. The components of G.L. and P.L. were analyzed under different extraction methods using ultra-performance liquid chromatography time-of-flight mass spectrometry (UPLC-Q-TOF/MS). Results showed that cassava leaf extracts are rich in bioactive metabolites such as D-(+)-mannose, trigonelline, rutin, kaempferol-3-

Indexed as

Anti-Inflammatory AgentsManihotAnimalsDermatitisDermisDisease Models, AnimalInterleukin-17MaleMiceMolecular Docking SimulationNetwork PharmacologyPlant ExtractsPlant LeavesProtein Structure, TertiaryProto-Oncogene Proteins B-rafProto-Oncogene Proteins c-aktAnti-Inflammatory AgentsInterleukin-17Plant ExtractsProto-Oncogene Proteins B-rafProto-Oncogene Proteins c-aktTumor Necrosis Factor-alphaanti-inflammatorycassavachemical compositionleaf extractstranscriptomics analysis

Identifiers

PMID40362388
PMCPMC12071432

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.