Evidence map›Paper›PMID 40362464›Full record

ArticleInternational journal of molecular sciences2025

Structural Insights into the Dynamics of Water in SOD1 Catalysis and Drug Interactions.

Ilkin Yapici, Arda Gorkem Tokur, Belgin Sever, Halilibrahim Ciftci, Ayse Nazli Basak, Hasan DeMirci

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ilkin YapiciDepartment of Molecular Biology and Genetics, Koc University, Istanbul 34450, Türkiye.ORCID 0000-0001-9686-4943
Arda Gorkem TokurDepartment of Molecular Biology and Genetics, Koc University, Istanbul 34450, Türkiye.ORCID 0009-0009-3478-8258
Belgin SeverDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir 26470, Türkiye.ORCID 0000-0003-4847-9711
Halilibrahim CiftciDepartment of Molecular Biology and Genetics, Burdur Mehmet Akif Ersoy University, Burdur 15030, Türkiye.ORCID 0000-0002-9796-7669
Ayse Nazli BasakSuna and İnan Kıraç Foundation, Neurodegeneration Research Laboratory (KUTTAM-NDAL), School of Medicine, Koc University, Istanbul 34450, Türkiye.ORCID 0000-0001-6977-2517
Hasan DeMirciDepartment of Molecular Biology and Genetics, Koc University, Istanbul 34450, Türkiye.ORCID 0000-0002-9135-5397

Funding

European Union's Horizon Europe research and innovation programme under the Marie Sktodowska-Curie grant agreement 101061939Scientific and Technological Research Council of Turkey (TÜBİTAK) 122Z429
6 · The paper itself

Abstract

Superoxide dismutase 1 (SOD1) is a crucial enzyme that protects cells from oxidative damage by converting superoxide radicals into H

Indexed as

Superoxide Dismutase-1WaterAmyotrophic Lateral SclerosisCatalysisCatalytic DomainCrystallography, X-RayHumansHydrogen BondingMolecular Docking SimulationMolecular Dynamics SimulationProtein ConformationSOD1 protein, humanSuperoxide Dismutase-1WaterAbl1 inhibitorsALSdrug designhSOD1molecular modelingradical scavengerstructural biologyX-ray crystallography

Identifiers

PMID40362464
PMCPMC12071975

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.