Evidence map›Paper›PMID 40362666›Full record

ReviewInternational journal of molecular sciences2025

Towards Precision in Sarcopenia Assessment: The Challenges of Multimodal Data Analysis in the Era of AI.

Valerio Caputo, Ivan Letteri, Silvano Junior Santini, Gaia Sinatti, Clara Balsano

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Observational
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Valerio CaputoDepartment of Life, Health and Environmental Sciences, University of L'Aquila, P.le Salvatore Tommasi, 67100 L'Aquila, Italy.ORCID 0000-0002-3503-3318
Ivan LetteriDepartment of Life, Health and Environmental Sciences, University of L'Aquila, P.le Salvatore Tommasi, 67100 L'Aquila, Italy.ORCID 0000-0002-3843-386X
Silvano Junior SantiniDepartment of Life, Health and Environmental Sciences, University of L'Aquila, P.le Salvatore Tommasi, 67100 L'Aquila, Italy.ORCID 0000-0001-6577-5892
Gaia SinattiDepartment of Life, Health and Environmental Sciences, University of L'Aquila, P.le Salvatore Tommasi, 67100 L'Aquila, Italy.ORCID 0000-0002-6474-6368
Clara BalsanoDepartment of Life, Health and Environmental Sciences, University of L'Aquila, P.le Salvatore Tommasi, 67100 L'Aquila, Italy.ORCID 0000-0002-9615-7031

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcopenia, a condition characterised by the progressive decline in skeletal muscle mass and function, presents significant challenges in geriatric healthcare. Despite advances in its management, complex etiopathogenesis and the heterogeneity of diagnostic criteria underlie the limited precision of existing assessment methods. Therefore, efforts are needed to improve the knowledge and pave the way for more effective management and a more precise diagnosis. To this purpose, emerging technologies such as artificial intelligence (AI) can facilitate the identification of novel and accurate biomarkers by modelling complex data resulting from high-throughput technologies, fostering the setting up of a more precise approach. Based on such considerations, this review explores AI's transformative potential, illustrating studies that integrate AI, especially machine learning and deep learning, with heterogeneous data such as clinical, anthropometric and molecular data. Overall, the present review will highlight the relevance of large-scale, standardised studies to validate biomarker signatures using AI-driven approaches.

Indexed as

Artificial IntelligencePrecision MedicineSarcopeniaBiomarkersData AnalysisHumansMachine LearningMuscle, SkeletalBiomarkersartificial intelligencecirculating biomarkerscirculating proteomediagnosismachine learningmetabolomemolecular markersmultimodal analysisnc-RNAssarcopenia

Identifiers

PMID40362666
PMCPMC12073030

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.