Evidence map›Paper›PMID 40364813›Full record

ArticleFrontiers in pediatrics2025

Neonatal spinal muscular atrophy with brain magnetic resonance imaging hypersignal: a case report.

Xiaolin Jieda, Chaoge Yang, Yue Wu, Rong Zhang, Wanting Xu, Wenbin Dong

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaolin Jieda *Department of Neonatology, Children's Medical Center, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Chaoge Yang *Department of Pediatrics, Southwest Medical University, Luzhou, China.
Yue WuDepartment of Neonatology, Children's Medical Center, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Rong ZhangDepartment of Neonatology, Children's Medical Center, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Wanting XuDepartment of Neonatology, Children's Medical Center, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Wenbin DongDepartment of Neonatology, Children's Medical Center, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal muscular atrophy (SMA) is an autosomal recessive genetic disorder marked by progressive, symmetrical muscle weakness and atrophy. While only a limited number of studies on human SMA have demonstrated brain involvement, there are also few reports detailing early brain MRI changes in SMA patients. In this paper, we present the case of a child whose initial symptom was limb hypotonia. The child's brain MRI revealed abnormal signal changes and genetic testing ultimately confirmed the diagnosis of SMA. By reviewing relevant literature, we aim to summarize the brain MRI signal changes observed in SMA patients and explore their possible mechanisms, with the goal of enhancing clinicians' ability to identify and treat neonatal SMA at an early stage.

Indexed as

brain MRIcase reportneonatalSMNspinal muscular atrophy (SMA)

Identifiers

PMID40364813
PMCPMC12069446

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.