Evidence map›Paper›PMID 40365293›Full record

ArticleTheranostics2025

AHCYL1 mediates the tumor-promoting effect of PREX2 in non-small cell lung carcinoma.

Mingjuan Lei, Yiu To Yeung, Wenna Nie, Ran Yang, Jian Li, Hanyong Chen, Ran Zhao, Kangdong Liu, Zigang Dong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mingjuan LeiDepartment of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Yiu To YeungChina-US (Henan) Hormel Cancer Institute, Zhengzhou, Henan, China.
Wenna NieChina-US (Henan) Hormel Cancer Institute, Zhengzhou, Henan, China.
Ran YangChina-US (Henan) Hormel Cancer Institute, Zhengzhou, Henan, China.
Jian LiChina-US (Henan) Hormel Cancer Institute, Zhengzhou, Henan, China.
Hanyong ChenThe Hormel Institute, University of Minnesota, MN, USA.
Ran ZhaoDepartment of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Kangdong LiuDepartment of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Zigang DongDepartment of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, Non-Small-Cell LungGuanine Nucleotide Exchange FactorsLung NeoplasmsAnimalsCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansMiceXenograft Model Antitumor AssaysGuanine Nucleotide Exchange FactorsPREX2 protein, humanAdenosylhomocysteinase Like 1 (AHCYL1)Cell growthGEF activityNSCLCPhosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger factor 2 (PREX2)

Identifiers

PMID40365293
PMCPMC12068309

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.