ArticleJournal of the American Heart Association2025
High Mortality and Complications in Patients Admitted With Takotsubo Cardiomyopathy With More Than Double Mortality in Men Without Improvement in Outcome Over the Years.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- A novel parameter for risk stratification in patients with takotsubo syndrome.American heart journal plus : cardiology research and practice · 2026Article
- Bridging Minds and Hearts by Exploring the Comorbidities Between Anxiety, Depression, and Takotsubo Cardiomyopathy: A Scoping Review.Journal of clinical medicine · 2026Review
- Article
- Third Year in Review, Fourth Year in Preview, and the 2025Journal of the American Heart Association · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTakotsubo cardiomyopathy continues to be a major cause of mortality and morbidity. The goal of this study was to evaluate the outcome data of patients with Takotsubo cardiomyopathy using a large inpatient database. METHODS AND
resultsWe used the Nationwide Inpatient Sample database for our study. We evaluated trends, mortality, and complications of patients admitted with Takotsubo cardiomyopathy from available years 2016 to 2020 in adults >18. A total of 199 890 patients with Takotsubo were found in our database with 83% being female and higher prevalence with age, White race, and highest income. Mortality was high at 6.5% with no significant improvement over the years studied. Furthermore, major complications were substantial. Cardiogenic shock occurred in 6.6%, atrial fibrillation in 20.7%, cardiac arrest in 3.4%, congestive heart failure in 35.9%, and stroke in 5.3%. Mortality was more than double in men in comparison to women (11.2% versus 5.5%).
conclusionsTakotsubo cardiomyopathy is associated with high mortality and complications with no improvement in outcome over the 5-year study with higher mortality in men. Further improvement in care is needed to improve outcomes.
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Registered trials
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