Evidence map›Paper›PMID 40366029›Full record

ArticleNucleic acids research2025

MOBHunter: a data integration platform for identification and classification of mobile genetic elements in microbial genomes.

Camila Rojas-Villalobos, Francisco J Ossandon, Camila Castillo-Vilcahuaman, Pedro Sepúlveda-Rebolledo, David Castro-Salinas, Abraham Zapata-Araya, Dilanaz Arisan, Tomás Perez-Acle, Francisco Issotta, Raquel Quatrini and 1 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. β-lactamase genes in clinical isolates of Capnocytophaga canimorsus and description of a novel class D β-lactamase, OXA-1422.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Camila Rojas-VillalobosCentro Científico y Tecnológico de Excelencia Ciencia & Vida, Santiago 8580704, Chile.
Francisco J OssandonCentro Científico y Tecnológico de Excelencia Ciencia & Vida, Santiago 8580704, Chile.
Camila Castillo-VilcahuamanCentro Científico y Tecnológico de Excelencia Ciencia & Vida, Santiago 8580704, Chile.
Pedro Sepúlveda-RebolledoCentro Científico y Tecnológico de Excelencia Ciencia & Vida, Santiago 8580704, Chile.
David Castro-SalinasPrograma de Doctorado en Informática Aplicada a Salud y Medio Ambiente, Escuela de Postgrado, Universidad Tecnológica Metropolitana, Santiago 8330300, Chile.
Abraham Zapata-ArayaCentro Científico y Tecnológico de Excelencia Ciencia & Vida, Santiago 8580704, Chile.
Dilanaz ArisanCentro Científico y Tecnológico de Excelencia Ciencia & Vida, Santiago 8580704, Chile.
Tomás Perez-AcleCentro Científico y Tecnológico de Excelencia Ciencia & Vida, Santiago 8580704, Chile.
Francisco IssottaCentro Científico y Tecnológico de Excelencia Ciencia & Vida, Santiago 8580704, Chile.
Raquel QuatriniCentro Científico y Tecnológico de Excelencia Ciencia & Vida, Santiago 8580704, Chile.ORCID 0000-0003-2600-2605
Ana Moya-BeltránDepartamento de Informática y Computación, Facultad de Ingeniería, Universidad Tecnológica Metropolitana, Santiago 7800002, Chile.ORCID 0000-0002-6924-5087

Funding

ANID 1221035ANID ANID/BASAL/FB210008ANID/BECAS/DOCTORADO NACIONAL 21241467Fondo VRID apoyo a congresos USS-FIN-24-CNGD-26PROYECTO FONDECYT POSTDOCTORADO 3140005PROYECTO FONDECYT POSTDOCTORADO 32300527Vicerrectoría de Investigación y Doctorados de la Universidad San Sebastián - Fondo USS-FIN-25-APCS-20Vicerrectoría de Investigación y Postgrado - Escuela de Postgrado - Universidad Tecnológica MetropolitanaVRID-Universidad San Sebastián PROYECTO/USS-FIN-23-PDOC-03USS
6 · The paper itself

Abstract

Horizontal gene transfer plays a critical role in microbial genome evolution and adaptation. Integrated foreign DNA fragments encompass various types of mobile genetic elements (MGEs), ranging from small transposons to conspicuous integrative and conjugative elements. These regions often confer advantageous traits, including antibiotic resistance or novel metabolic capabilities, and contain foreign sequence signatures and hallmark genes such as transposases, integrases, etc. While bioinformatic tools target specific MGE subsets using alignments, compositional signatures, or diagnostic gene mapping, no single platform offers a unified framework for comprehensive, evidence-based, MGE identification and classification. To address this challenge, we developed MOBHunter, an advanced bioinformatic pipeline that consolidates standalone tools and in-house algorithms. Unlike basic tool concatenation, MOBHunter yields consensus identifications, score-supported classifications, and enhanced web visualizations. The platform reduces end user analysis time by integrating data collection, processing, and interpretation into a unified workflow. It delivers robust classifications of MGEs into distinct families and provides a comprehensive overview of the flexible regions of any given input genome. URL: https://informatica.utem.cl/mobhunter/.

Indexed as

Computational BiologyGenome, MicrobialInterspersed Repetitive SequencesSoftwareAlgorithmsDNA Transposable ElementsGene Transfer, HorizontalGenome, BacterialGenomicsDNA Transposable Elements

Identifiers

PMID40366029
PMCPMC12230661

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.