Evidence map›Paper›PMID 40366598›Full record

ReviewCurrent topics in behavioral neurosciences2025

Insights into Overlapping Brain Networks for Anxiety and Alcohol Use Disorders.

Nicole L Zabik, Jennifer Urbano Blackford

Abstract readReview
In one paragraph

Review in Current topics in behavioral neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicole L ZabikMunroe-Meyer Institute, University of Nebraska Medical Center, Omaha, NE, USA.
Jennifer Urbano BlackfordMunroe-Meyer Institute, University of Nebraska Medical Center, Omaha, NE, USA. jblackford@unmc.edu.

Funding

VAREC Research CoreP60AA031124 · NIAAA · VANDERBILT UNIVERSITY · PI Erin Calipari · 2024 to 2026
$7.1M
Sex differences in BNST networks during early abstinence in AUDR01AA029127 · NIAAA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BLACKFORD, JENNIFER URBANO · 2021 to 2025
$3.0M
Negative reinforcement in early abstinence from an alcohol use disorderF32AA032170 · NIAAA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Nicole Lauren Zabik · 2024 to 2026
$164k
NIAAA NIH HHS F32 AA032170NIAAA NIH HHS P60 AA031124NIAAA NIH HHS R01 AA029127
6 · The paper itself

Abstract

Alcohol use disorder (AUD) is a debilitating condition affecting over 30 million Americans. AUD commonly co-occurs with other disorders, like other substance use disorders, trauma-related disorders, and anxiety disorders. Of the numerous co-occurring disorders, anxiety disorders are the most pervasive: anxiety disorders serve as a risk factor for developing AUD, emerge as co-occurring disorders that maintain alcohol drinking, and impede the effectiveness of treatments for AUD. Anxiety, therefore, shapes the development, course, and treatment of AUDs. AUDs can also increase anxiety, suggesting a complex, bidirectional relation between alcohol use and anxiety. The intersection of AUDs and anxiety is also supported by their overlapping neural circuits, specifically neural circuits involved in stress responding, reward processing, and cognitive control. The current review highlights findings from several decades of research on how anxiety impacts the brain and treatment outcomes in AUDs. We also provide important considerations for future research, with the goal of reducing the shame and burden of alcohol use for individuals with AUD and their families.

Indexed as

AlcoholismAnxietyAnxiety DisordersBrainNerve NetHumansAlcohol use disordersAnxiety disordersNegative affectNeuroimaging

Identifiers

PMID40366598
PMCPMC12353971

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.