Evidence map›Paper›PMID 40366609›Full record

ArticleEuropean journal of epidemiology2025

Outdoor air pollution, road traffic noise, and allostatic load in children aged 6-11 years: evidence from six European cohorts.

Yuchan Mou, Michelle Sofia Wilhelmina Kusters, Oliver Robinson, Lea Maitre, Rosemary R C McEachan, Wen Lun Yuan, Norun Hjertager Krog, Sandra Andrušaitytė, Mariona Bustamante, Montserrat de Castro Pascual and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Yuchan MouISGlobal, Barcelona, Spain.
Michelle Sofia Wilhelmina KustersISGlobal, Barcelona, Spain.
Oliver RobinsonΜedical Research Council Centre for Environment and Health, Imperial College London, London, UK.
Lea MaitreISGlobal, Barcelona, Spain.
Rosemary R C McEachanBradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK.
Wen Lun YuanInserm, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Université Paris Cité and Université Sorbonne Paris Nord, 75004, Paris, France.
Norun Hjertager KrogDivision of Climate and Environmental Health, Department of Air Quality and Noise, Norwegian Institute of Public Health, Oslo, Norway.
Sandra AndrušaitytėDepartment of Environmental Sciences, Vytautas Magnus University, Kaunas, Lithuania.
Mariona BustamanteISGlobal, Barcelona, Spain.
Montserrat de Castro PascualISGlobal, Barcelona, Spain.
Audrius DedeleDepartment of Environmental Sciences, Vytautas Magnus University, Kaunas, Lithuania.
John WrightBradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK.
Regina GrazulevicieneDepartment of Environmental Sciences, Vytautas Magnus University, Kaunas, Lithuania.
Gunn Marit AasvangDivision of Climate and Environmental Health, Department of Air Quality and Noise, Norwegian Institute of Public Health, Oslo, Norway.
Johanna LepeuleInserm U 1209, CNRS UMR 5309, Team of Environmental Epidemiology Applied to Development and Respiratory Health, Institute for Advanced Biosciences, University Grenoble Alpes, Grenoble, France.
Mark NieuwenhuijsenISGlobal, Barcelona, Spain.
Henning TiemeierDepartment of Social and Behavioral Sciences, Harvard TH Chan School of Public Health, Boston, MA, USA.
Martine VrijheidISGlobal, Barcelona, Spain.
Errol M ThomsonEnvironmental Health Science and Research Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Canada.
Mònica GuxensISGlobal, Barcelona, Spain. monica.guxens@isglobal.org.ORCID http://orcid.org/0000-0002-8624-0333

Funding

Agencia Estatal de Investigación PRE2020-092005Agencia Estatal de Investigación RYC2022-036475-IEuropean Social Fund Plus PRE2020-092005European Social Fund Plus RYC2022-036475-IHorizon 2020 Framework Programme 874739Instituto de Salud Carlos III CPII18/00018Koninklijke Nederlandse Akademie van Wetenschappen TMB416UK Research and Innovation MR/S03532X/1
6 · The paper itself

Abstract

Emerging evidence suggests that exposure to air pollutants and road traffic noise triggers stress responses, which mediate physiological responses in multiple organs and tissues. However, epidemiological study in children is sparse. We aimed to evaluate whether outdoor air pollution and road traffic noise are associated with physiological response measured by allostatic load in children. We studied 919 children aged 6-11 years from the HELIX (Human Early Life Exposome) cohort in 6 European countries with 19 biomarkers assessed in four physiological systems-cardiovascular, metabolic, immune/inflammation, and neuroendocrine systems. We then calculated both count-based and continuous scores for each physiological system and generated allostatic load scores (range 0-19). Exposure to air pollution (NO

Indexed as

Air PollutantsAir PollutionAllostasisEnvironmental ExposureNoise, TransportationBiomarkersChildCohort StudiesEuropeFemaleHumansMaleParticulate MatterTraffic-Related PollutionAir PollutantsBiomarkersParticulate MatterAir pollutionAllostasisChildrenEnvironmental exposureNoiseParticulate matterTransportation

Identifiers

PMID40366609
PMCPMC12170719

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.