Evidence map›Paper›PMID 40368822›Full record

ArticleThe Journal of veterinary medical science2025

Exercise-induced mild rhabdomyolysis associated with oclacitinib in a dog.

Junya Hirashima, Yui Kobatake, Saki Nomura, Naoki Iwasa, Momoko Narita, Sadatoshi Maeda, Satoshi Takashima, Naohito Nishii

Abstract readCase Reports
In one paragraph

Article in The Journal of veterinary medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Junya HirashimaFaculty of Applied Biological Sciences, Gifu University, Gifu, Japan.
Yui KobatakeFaculty of Applied Biological Sciences, Gifu University, Gifu, Japan.
Saki NomuraTanahashi Animal Clinic, Gifu, Japan.
Naoki IwasaHashima Animal Hospital, Gifu, Japan.
Momoko NaritaFaculty of Applied Biological Sciences, Gifu University, Gifu, Japan.
Sadatoshi MaedaFaculty of Applied Biological Sciences, Gifu University, Gifu, Japan.
Satoshi TakashimaFaculty of Applied Biological Sciences, Gifu University, Gifu, Japan.
Naohito NishiiFaculty of Applied Biological Sciences, Gifu University, Gifu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A four-year-old Toy Poodle treated with oclacitinib for one year presented with transient myoglobinuria associated with elevated serum creatine kinase (CK) levels only after exercise. An association between myoglobinuria and oclacitinib was suspected. An exercise stress test with or without oclacitinib was repeated twice on different days. Myoglobinuria and increased serum CK levels occurred only after testing with oclacitinib. The dog was diagnosed with exercise-induced mild rhabdomyolysis, which was presumably provoked by oclacitinib based on the results of the exercise stress tests. Rhabdomyolysis was considered an idiosyncratic adverse event for oclacitinib. This is the first report of exercise-induced mild rhabdomyolysis associated with oclacitinib in a dog.

Indexed as

Dog DiseasesPhysical Conditioning, AnimalPyrimidinesRhabdomyolysisSulfonamidesAnimalsCreatine KinaseDogsMaleMyoglobinuriaCreatine KinasePyrimidinesSulfonamidesdogoclacitinibrhabdomyolysis

Identifiers

PMID40368822
PMCPMC12246631

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.