Evidence map›Paper›PMID 40368990›Full record

ArticleScientific reports2025

Association of coagulation-related indicators with postoperative venous thromboembolism occurrence in patients with pituitary tumors.

Yi Xiang, Ya Wu, Huan Liu, Zheng Chen, JinYu Pan

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yi XiangChongqing General Hospital, Chongqing University, 118 Star Avenue, Liangjiang New Area, Chongqing, China.
Ya WuThe Second Clinical College of the Army Medical University, Chongqing, China.
Huan LiuThe Second Clinical College of the Army Medical University, Chongqing, China.
Zheng ChenThe Second Clinical College of the Army Medical University, Chongqing, China.
JinYu PanChongqing General Hospital, Chongqing University, 118 Star Avenue, Liangjiang New Area, Chongqing, China. 1130284281@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to analyze risk factors for postoperative VTE in pituitary tumor resection patients, focusing on coagulation indicators and their predictive value. This study collected clinical data from 300 patients who underwent pituitary adenoma resection from January 2021 to August 2023 in the Department of Neurosurgery, the Second Clinical College of the Army Medical University, China. Logistic regression modeling was used to identify risk factors for VTE. Restricted cubic spline curves were used to characterize the dose-response relationship between coagulation-related indicators and the risk of venous thromboembolism. The area under the curve (AUC) was calculated using the receiver operating characteristic (ROC) curve to evaluate the predictive power of coagulation-related indicators. Multivariate analysis showed that D-dimer, platelet count and hemoglobin (Hb) were significant predictors of VTE with OR (95% CI) of 1.967 (1.441-2.808), 1.020 (1.013-1.029), and 0.952 (0.914-0.994), respectively. The AUCs for D-dimer, Platelet Count, and Hb were 0.708, 0.731, and 0.712, respectively. The AUC for combining the three coagulation indices was the largest, 0.838. The combined use of D-dimer, Hb, and platelet count can identify high-risk patients early, enabling timely implementation of antithrombotic strategies.

Indexed as

Blood CoagulationPituitary NeoplasmsPostoperative ComplicationsVenous ThromboembolismAdenomaAdultAgedChinaFemaleFibrin Fibrinogen Degradation ProductsHemoglobinsHumansMaleMiddle AgedPlatelet CountRetrospective StudiesFibrin Fibrinogen Degradation Productsfibrin fragment DHemoglobinsD-dimerHemoglobinPituitary tumorPlatelet countVenous thromboembolism

Identifiers

PMID40368990
PMCPMC12078525

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.