Evidence map›Paper›PMID 40369700›Full record

ReviewJournal of cannabis research2025

Use of industrial hemp byproducts in ruminants: a review of the nutritional profile, animal response, constraints, and global regulatory environment.

Agung Irawan, Hunter Buffington, Serkan Ates, Massimo Bionaz

Abstract readReview
In one paragraph

Review in Journal of cannabis research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Nutritive Value and Cannabinoid Potency of Diverse Hemp (Journal of agricultural and food chemistry · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Agung IrawanOregon State University, Corvallis, OR, 97331, USA.ORCID http://orcid.org/0000-0003-1179-0469
Hunter BuffingtonAgriculture Policy Solutions, Loveland, CO, 80538, USA.
Serkan AtesOregon State University, Corvallis, OR, 97331, USA.ORCID http://orcid.org/0000-0001-6825-3248
Massimo BionazOregon State University, Corvallis, OR, 97331, USA. massimo.bionaz@oregonstate.edu.ORCID http://orcid.org/0000-0002-0674-1892

Funding

National Institute of Food and Agriculture 2021-68008-34099
6 · The paper itself

Abstract

backgroundThe legalization of industrial hemp, Cannabis sativa L., which contains < 0.3% ∆

methodWe provide an overview of the nutritional characteristics of the various hemp byproducts and provide a meta-analysis of 26 empirical studies investigating the use of hemp byproducts on ruminants. Using those studies, we delved into a comprehensive assessment regarding the effects of HSB and SHB on the health and performance of the animals.

resultsOverall, HSB and SHB possess excellent nutritional profiles due to their high protein content and, particularly for HSB, desirable fatty acids profile can partially replace protein-source ingredients such as soybean meal, dried distillers' grains with soluble, canola meal, and alfalfa in the diets of ruminants. These byproducts contain diverse phytochemicals with antioxidants, anti-inflammatory, and antimicrobial properties. Data do not reveal any significant concern for the health of the animals fed hemp byproducts and, with few exceptions, the data do not indicate a substantial effect on performance; dietary inclusion of HSB, however, has a deleterious impact on rumen fermentation and nutrient digestibility when given as raw HSB without dehulling, reducing the growth performance of meat-producing ruminants. On the other hand, SHB has low palatability overall but does not impair production performance.

conclusionsAlthough they can be promising feed ingredients for ruminants, their present use as feed ingredients is limited by the residuals of THC and CBD. Our comprehensive review of the current legal status of hemp byproducts worldwide highlighted a complex scenario with some countries allowing the use of hemp byproducts as feed ingredients, some with no clear regulations, and some countries where a path for the regulation has started, such as the US. Still, no hemp byproducts are yet legal as a feed ingredient for ruminants.

Indexed as

Cannabis sativaFeed alternativeHemp byproductIndustrial hempRuminants

Identifiers

PMID40369700
PMCPMC12076842

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.