ArticleFrontiers in pediatrics2025
The clinical value of autologous platelet-rich plasma extraction and injection as an adjunct to urethroplasty in the treatment of penile hypospadias in children.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effect of autologous platelet-rich treatment in hypospadias repair: a systematic review and meta-analysis.Pediatric surgery international · 2026Pooled it
- The ripple effect of stigmatization on children with congenital hypospadias: impacts on psychological and behavioral aspects.Frontiers in public health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate the clinical efficacy and safety of autologous platelet-rich plasma (PRP) as an adjunctive treatment for penile hypospadias repair in children, and to explore its independent role in reducing postoperative complications. Methods: We retrospectively analyzed clinical data from 103 pediatric patients undergoing penile hypospadias repair between December 2019 and December 2021 at the Affiliated Hospital of Zunyi Medical University. All patients received standard penile straightening and tubularized incised plate (TIP) urethroplasty. Patients in the study group ( Results: No significant differences were observed between groups regarding operation time, postoperative ambulation time, or length of hospital stay ( Conclusion: Adjunctive autologous PRP treatment in pediatric penile hypospadias repair effectively alleviates postoperative pain, enhances wound healing, significantly reduces short-term complications, and improves surgical success rates. Future randomized, multicenter trials with extended follow-up periods are required to further evaluate long-term outcomes and to compare PRP efficacy directly with other biomaterials used in urethroplasty.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.