Evidence map›Paper›PMID 40371338›Full record

ArticleFrontiers in pharmacology2025

SuoquanYishen formula improves renal cellular senescence by inhibiting YTHDF1-Rubicon axis to promote autophagy in diabetic kidney disease.

Zijie Yan, Lin Zhang, Tianpeng Ma, Yong Yuan, Yu Kang, Shuman Liu, BoCen Chen, Kai Li, Man Xiao, Yiqiang Xie

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. The Role of Renal Cell Senescence in Diabetic Kidney Disease: Mechanisms and Therapeutic Advances.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zijie Yan *College of Traditional Chinese Medicine, Hainan Medical University, Haikou, China.
Lin Zhang *College of Traditional Chinese Medicine, Hainan Medical University, Haikou, China.
Tianpeng Ma *College of Traditional Chinese Medicine, Hainan Medical University, Haikou, China.
Yong YuanSanya Hospital of Traditional Chinese Medicine, Sanya, Hainan, China.
Yu KangHeilongjiang Academy of Traditional Chinese Medicine, Harbin, China.
Shuman LiuCollege of Traditional Chinese Medicine, Hainan Medical University, Haikou, China.
BoCen ChenKey Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China.
Kai LiCollege of Traditional Chinese Medicine, Hainan Medical University, Haikou, China.
Man XiaoKey Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China.
Yiqiang XieCollege of Traditional Chinese Medicine, Hainan Medical University, Haikou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SuoquanYishen formula (SQYSF), a traditional Chinese herbal prescription for treating diabetic kidney disease (DKD), has demonstrated clinical efficacy in lowering blood glucose and alleviating renal damage. Emerging evidence implicates cellular senescence as a critical contributor to DKD progression. This study aimed to elucidate the mechanism by which SQYSF improves renal cellular senescence using both

Indexed as

autophagycellular senescencediabetic kidney diseasem6A modificationRubiconSuoquanYishen formulatraditional Chinese medicineYTHDF1

Identifiers

PMID40371338
PMCPMC12075247

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.