Evidence mapPaperPMID 40372010Full record

ArticleJournal of the American Chemical Society2025

Pools of Independently Cycling Inositol Phosphates Revealed by Pulse Labeling with

Geun-Don Kim, Guizhen Liu, Danye Qiu, Maria Giovanna De Leo, Navin Gopaldass, Jacques Hermes, Jens Timmer, Adolfo Saiardi, Andreas Mayer, Henning Jacob Jessen

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. EstablishingAnalytical chemistry · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Geun-Don KimDépartement d'immunobiologie, Université de Lausanne, CH-1066 Epalinges, Switzerland.ORCID 0000-0002-3580-2471
Guizhen LiuInstitute of Organic Chemistry, University of Freiburg, 79104 Freiburg, Germany.
Danye QiuInstitute of Organic Chemistry, University of Freiburg, 79104 Freiburg, Germany.
Maria Giovanna De LeoDépartement d'immunobiologie, Université de Lausanne, CH-1066 Epalinges, Switzerland.
Navin GopaldassDépartement d'immunobiologie, Université de Lausanne, CH-1066 Epalinges, Switzerland.
Jacques HermesCIBSS─Centre for Integrative Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany.
Jens TimmerCIBSS─Centre for Integrative Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany.
Adolfo SaiardiMedical Research Council, Laboratory for Molecular Cell Biology, University College London, WC1E 6BT London, U.K.ORCID 0000-0002-4351-0081
Andreas MayerDépartement d'immunobiologie, Université de Lausanne, CH-1066 Epalinges, Switzerland.ORCID 0000-0001-6131-313X
Henning Jacob JessenInstitute of Organic Chemistry, University of Freiburg, 79104 Freiburg, Germany.ORCID 0000-0002-1025-9484

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inositol phosphates control many central processes in eukaryotic cells including nutrient availability, growth, and motility. Kinetic resolution of a key modulator of their signaling functions, the turnover of the phosphate groups on the inositol ring, has been hampered by slow uptake, high dilution, and constraining growth conditions in radioactive pulse-labeling approaches. Here, we demonstrate a rapid (seconds to minutes) and nonradioactive labeling strategy of inositol polyphosphates through

Indexed as

Inositol PhosphatesWaterHumansIsotope LabelingOxygen IsotopesSaccharomyces cerevisiaeInositol PhosphatesOxygen-18Oxygen IsotopesWater

Identifiers

PMID40372010
PMCPMC12123611

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.