Evidence map›Paper›PMID 40374731›Full record

ArticleNature immunology2025

GFI1-driven transcriptional and epigenetic programs maintain CD8

M Zeeshan Chaudhry, Evelyn Chen, Hiu On Man, Aneesha Jones, Renae Denman, Huiyang Yu, Qiutong Huang, Adrian Ilich, Jaring Schreuder, Severine Navarro and 2 more

Abstract read
In one paragraph

Article in Nature immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

M Zeeshan ChaudhryThe University of Queensland Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia. mz.chaudhry@uq.edu.au.ORCID http://orcid.org/0000-0002-1372-4257
Evelyn ChenThe University of Queensland Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia.
Hiu On ManIan Frazer Centre for Children's Immunotherapy Research, Child Health Research Centre, The University of Queensland, Woolloongabba, Queensland, Australia.
Aneesha JonesThe University of Queensland Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia.
Renae DenmanThe University of Queensland Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia.ORCID http://orcid.org/0000-0001-9695-8528
Huiyang YuThe University of Queensland Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia.ORCID http://orcid.org/0000-0002-3670-7898
Qiutong HuangThe University of Queensland Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia.
Adrian IlichQIMR Berghofer Medical Research, Herston, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0001-7577-5212
Jaring SchreuderThe University of Queensland Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia.ORCID http://orcid.org/0000-0002-7579-0006
Severine NavarroQIMR Berghofer Medical Research, Herston, Brisbane, Queensland, Australia.
Zewen K TuongIan Frazer Centre for Children's Immunotherapy Research, Child Health Research Centre, The University of Queensland, Woolloongabba, Queensland, Australia.ORCID http://orcid.org/0000-0002-6735-6808
Gabrielle T BelzThe University of Queensland Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia. g.belz@uq.edu.au.ORCID http://orcid.org/0000-0002-9660-9587

Funding

Department of Education and Training | Australian Research Council (ARC) DP200101058, DP230101156, FL240100130Department of Health | National Health and Medical Research Council (NHMRC) 1165443, 1122277, 1054925, 1135898, 2008542
6 · The paper itself

Abstract

Long-lived memory CD8

Indexed as

CD8-Positive T-LymphocytesDNA-Binding ProteinsEpigenesis, GeneticLymphocytic ChoriomeningitisMemory T CellsTranscription FactorsAnimalsCell ProliferationImmunologic MemoryLymphocytic choriomeningitis virusMiceMice, Inbred C57BLMice, KnockoutMuromegalovirusT-Box Domain ProteinsTranscription, GeneticDNA-Binding ProteinsEomes protein, mouseGfi1 protein, mouseT-Box Domain ProteinsTranscription Factors

Identifiers

PMID40374731
PMCPMC12133582

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.