SynthesisBMC musculoskeletal disorders2025
Pain management of hip osteoarthritis with corticosteroids vs injection therapies: a systematic review and meta-analysis.
Synthesis in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Endocannabinoid Tone and Oxylipins in Rheumatoid Arthritis and Osteoarthritis-A Novel Target for the Treatment of Pain and Inflammation?International journal of molecular sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionOsteoarthritis (OA) is the most common degenerative joint disease, characterized by chronic pain and articular cartilage damage. Hip OA is characterized by the progressive breakdown of articular cartilage within the hip, particularly the hip joints ball and socket structure, Hip OA leads to joint pain, stiffness and causes functional limitations.
aimTo analyse the effectiveness of intra-articular corticosteroids (IA CS) use against other injection therapies for the symptomatic management of hip OA.
methodsPROSPERO registered-CRD42024526221. Medline, Embase, Scopus and Web of Science were searched for trials. INCLUSION CRITERIA: Adults with symptomatic hip OA, randomised trials for treatment of hip OA with IA injection methods. Studies must involve comparators and the outcome measure must include a measurement of pain such as Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) or the visual analogue scale (VAS). Cochrane risk of bias and JBI critical appraisal tools assessed risk of bias. RevMan was used for creation of statistical figures within the meta-analysis.
resultsData extracted in the systematic review presented improvements on pain, function, stiffness, and overall scores using WOMAC and VAS scales. However, data from the meta-analysis indicates that there is no statistical significance (significance is a p value < 0.05) between corticosteroids and placebo or hyaluronic acid (HA). Meta-analyses produced p values of 0.05 when comparing CS and placebo WOMAC pain scores at 2 months, CS and HA overall WOMAC at 6 months-p value of 0.46. WOMAC stiffness and function scores between CS and placebo at 2 months-p value of 0.05 and 0.08, thus statistically insignificant.
conclusionThis meta-analysis shows that IA corticosteroid injections for hip OA don't provide statistically significant symptomatic improvement for patients compared to placebo. Showing the urgent need to assess other therapies in hip OA treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.