Evidence map›Paper›PMID 40375335›Full record

ReviewEuropean journal of medical research2025

Applications of machine learning and deep learning in musculoskeletal medicine: a narrative review.

Martina Feierabend, Julius Michael Wolfgart, Maximilian Praster, Marina Danalache, Filippo Migliorini, Ulf Krister Hofmann

Abstract readReview
In one paragraph

Review in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Optimizing the mathematical model and technical standards for unilateral biportal endoscopic spinal surgery through machine learning-based video analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Review
  3. Observational
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Martina FeierabendMetabolic Reconstruction and Flux Modelling, University of Cologne, Zülpicher Str. 47b, 50674, Cologne, Germany. mfeierab@uni-koeln.de.
Julius Michael WolfgartDepartment of Orthopaedic, Trauma, and Reconstructive Surgery, RWTH University Hospital, 52074, Aachen, Germany.
Maximilian PrasterDepartment of Orthopaedic, Trauma, and Reconstructive Surgery, Division of Arthroplasty and Tumour Surgery, RWTH University Hospital, 52074, Aachen, Germany.
Marina DanalacheDepartment of Orthopaedic Surgery, University Hospital Tübingen, Hoppe-Seyler Straße 3, 72076, Tübingen, Germany.
Filippo MiglioriniDepartment of Orthopaedic and Trauma Surgery, Academic Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of the Paracelsus Medical University, 39100, Bolzano, Italy.
Ulf Krister HofmannDepartment of Orthopaedic, Trauma, and Reconstructive Surgery, Division of Arthroplasty and Tumour Surgery, RWTH University Hospital, 52074, Aachen, Germany.ORCID http://orcid.org/0000-0003-0589-6654

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI), with its technologies such as machine perception, robotics, natural language processing, expert systems, and machine learning (ML) with its subset deep learning, have transformed patient care and administration in all fields of modern medicine. For many clinicians, however, the nature, scope, and resulting possibilities of ML and deep learning might not yet be fully clear. This narrative review provides an overview of the application of ML and deep learning in musculoskeletal medicine. It first introduces the concept of AI and machine learning and its associated fields. Different machine concepts such as supervised, unsupervised and reinforcement learning will then be presented with current applications and clinical perspective. Finally deep learning applications will be discussed. With significant improvements over the last decade, ML and its subset deep learning today offer potent tools for numerous applications to implement in clinical practice. While initial setup costs are high, these investments can reduce workload and cost globally. At the same time, many challenges remain, such as standardisation in data labelling and often insufficient validity of the obtained results. In addition, legal aspects still will have to be clarified. Until good analyses and predictions are obtained by an ML tool, patience in training and suitable data sets are required. Awareness of the strengths of ML and the limitations that lie within it will help put this technique to good use.

Indexed as

Deep LearningMachine LearningMusculoskeletal DiseasesArtificial IntelligenceHumansArtificial intelligenceMachine learningOrthopaedicsReinforcement learningSupervised learningTraumatologyUnsupervised learning

Identifiers

PMID40375335
PMCPMC12080048

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.