Evidence mapPaperPMID 40375701Full record

ReviewCurrent cardiology reviews2026

Pharmacological Foundation and Novel Insights of Resveratrol in Cardiovascular System: A Review.

Ruchi Tiwari, Gaurav Tiwari, Anju Singh, Namdev Dhas

Abstract readReview
In one paragraph

Review in Current cardiology reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ruchi TiwariDepartment of Pharmacy, PSIT-Pranveer Singh Institute of Technology, NH 19, Kanpur, 209305, Bhauti, Uttar Pradesh, India.ORCID 0000-0001-6897-3472
Gaurav TiwariDepartment of Pharmacy, PSIT-Pranveer Singh Institute of Technology, NH 19, Kanpur, 209305, Bhauti, Uttar Pradesh, India.ORCID 0000-0003-2200-737X
Anju SinghUniversity Institute of Pharmacy, Chhatrapati Shahu Ji Maharaj University (Formerly Kanpur University), Kanpur, 208024, Uttar Pradesh, India.ORCID 0009-0006-5534-0098
Namdev DhasDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE), Manipal, Udupi, 576104, Karnataka State, India.ORCID 0000-0002-9852-2653

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research into drugs that can enhance cardiovascular health has been sparked by the rising prevalence of cardiovascular illnesses (CVDs). In addition to its anti-inflammatory and antioxidant qualities, Resveratrol (RES) is well known for its capacity to increase endothelial NO synthase (eNOS) activity. This page summarises RES's wide effects on energy metabolism, resilience to stress, exercise mimicking, circadian rhythm, lifespan control, and microbiome composition. This article addresses the poor and contradictory results shown in preclinical and clinical trials provides an update on the cardiovascular preventive properties of RES. The activation of AMP-activated protein kinase (AMPK), silent information regulator 1 (SIRT1), and natural antioxidant enzymes is associated with some of the positive effects of RES on the cardiovascular system. A microarray data summary indicates a strong correlation between the heart's reaction to calorie restriction and the transcriptional responses to RES. RES has been demonstrated to reduce contractile dysfunction, cardiac remodelling, and hypertrophy in several animal models of heart failure. Its preventive properties are believed to be due to several molecular pathways, including the suppression of prohypertrophic signalling molecules, enhancement of cardiac Ca

Indexed as

AntioxidantsCardiovascular DiseasesCardiovascular SystemStilbenesAnimalsHumansResveratrolAntioxidantsResveratrolStilbenesatherosclerosiscalorie restrictioncardioprotection.cholesterolheart failurehypertensioninflammationlipoproteinsResveratrol

Identifiers

PMID40375701
PMCPMC12951065

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.