Evidence map›Paper›PMID 40375992›Full record

ArticleFrontiers in immunology2025

Anti-tumor effect and immune-related mechanism study of compound aluminum sulfate injection in transplanted tumor-bearing mice.

Zhenwei Shi, Zhifa Xia, Songtao Huang, Zeteng Chen, Fan Yin, Haili Xin, Fenghua Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhenwei Shi *Medical School of Chinese People's Liberation Army General Hospital, Beijing, China.
Zhifa Xia *Medical School of Chinese People's Liberation Army General Hospital, Beijing, China.
Songtao HuangMedical School of Chinese People's Liberation Army General Hospital, Beijing, China.
Zeteng ChenMedical School of Chinese People's Liberation Army General Hospital, Beijing, China.
Fan YinThe Second Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China.
Haili XinDepartment of Pharmacy, Medical Supplies Center, Chinese People's Liberation Army General Hospital, Beijing, China.
Fenghua XuPharmaceutical Sciences Research Division, Department of Pharmacy, Medical Supplies Center, Chinese People's Liberation Army General Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the antitumor and immunomodulatory effects of compound aluminum sulfate (CAS) solution in murine melanoma models. Using syngeneic B16-F10 and B16-OVA tumor models, we demonstrate that intratumoral CAS injection significantly inhibits primary tumor growth and lung metastasis. Flow cytometry analysis reveals that CAS treatment increases splenic populations of CD3

Indexed as

Alum CompoundsAntineoplastic AgentsLung NeoplasmsMelanoma, ExperimentalAnimalsCell Line, TumorCytokinesFemaleKiller Cells, NaturalMiceMice, Inbred C57BLAlum Compoundsaluminum sulfateAntineoplastic AgentsCytokinesanti-tumor effectcompound aluminum sulfate injectionimmunomodulatormelanomametastasis

Identifiers

PMID40375992
PMCPMC12078244

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.