ArticleFrontiers in neurology2025
Predictive value of the fibrinogen-to-albumin ratio for hemorrhagic transformation following intravenous thrombolysis in ischemic stroke: a retrospective propensity score-matched analysis.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Association between fibrinogen-albumin ratio and outcomes in myocardial infarction: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2026Article
- The Ratio Paradox in Stroke Prognosis: Abundant Evidence, Absent Utility.Translational stroke research · 2025Article
- Serum Biomarkers in Acute Ischemic Stroke: Clinical Applications and Emerging Insights.Journal of clinical medicine · 2025Review
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Authors and funding
3 authors.
Funding
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Abstract
Objective: This study aimed to explore the factors associated with hemorrhagic transformation (HT) in acute ischemic stroke patients after intravenous thrombolysis (IVT), with a specific focus on the relationship with the post-thrombolysis fibrinogen-to-albumin ratio (FAR). Methods: The clinical records of 569 acute ischemic stroke (AIS) patients admitted to our department from 2020 to 2023 were retrospectively analyzed. All eligible patients were stratified into HT and non-HT (NHT) groups. Propensity score matching (PSM) was performed between the two groups. Receiver operating characteristic (ROC) curves were used to assess the predictive performance of the FAR, determining the optimal predictive value. Results: Ultimately, 142 patients were included, with 71 in the HT group and 71 in the NHT group. After propensity score matching, a significant association was observed between the FAR and HT ( Conclusion: In ischemic stroke patients undergoing IVT, the FAR may serve as a promising biochemical marker for predicting HT following treatment.
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