Evidence map›Paper›PMID 40376201›Full record

ArticleBiomaterials research2025

Breaking the Chains of Therapeutic Blockade: Pyroptosis-Induced Photothermal-Chemotherapy with Targeted Nanoprobes in Triple-Negative Breast Cancer.

Zuying Li, Kexiao Yu, Youde Cao, Hui Yuan, Lingcheng Wu, Linyan Xiong, Yi Tang, Bing Liang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zuying LiDepartment of Ultrasound of Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Engineering Research Center of Stem Cell Therapy, Children's Hospital of Chongqing Medical University, Chongqing 400014, P. R. China.
Kexiao YuDepartment of Orthopedics, Chongqing Traditional Chinese Medicine Hospital, The First Affiliated Hospital of Chongqing University of Chinese Medicine, Chongqing 400021, P. R. China.
Youde CaoDepartment of Pathology from College of Basic Medicine, and Molecular Medicine Diagnostic & Testing Center, and Department of Clinical Pathology Laboratory of Pathology Diagnostic Center, Chongqing Medical University, Chongqing 400016, P. R. China.
Hui YuanDepartment of Pathology from College of Basic Medicine, and Molecular Medicine Diagnostic & Testing Center, and Department of Clinical Pathology Laboratory of Pathology Diagnostic Center, Chongqing Medical University, Chongqing 400016, P. R. China.
Lingcheng WuDepartment of Ultrasound & Chongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, P. R. China.
Linyan XiongDepartment of Pathology from College of Basic Medicine, and Molecular Medicine Diagnostic & Testing Center, and Department of Clinical Pathology Laboratory of Pathology Diagnostic Center, Chongqing Medical University, Chongqing 400016, P. R. China.
Yi TangDepartment of Ultrasound of Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Engineering Research Center of Stem Cell Therapy, Children's Hospital of Chongqing Medical University, Chongqing 400014, P. R. China.
Bing LiangDepartment of Pathology from College of Basic Medicine, and Molecular Medicine Diagnostic & Testing Center, and Department of Clinical Pathology Laboratory of Pathology Diagnostic Center, Chongqing Medical University, Chongqing 400016, P. R. China.ORCID https://orcid.org/0000-0002-5007-2825

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an important clinical need and social significance, especially for young patients, to explore a new breast-conserving strategy that is not dependent on biomarkers for anti-triple-negative breast cancer. Disulfiram, historically employed for the treatment of chronic alcoholism, has recently emerged as a promising antitumor agent in combination with Cu

Identifiers

PMID40376201
PMCPMC12079191

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.