Evidence map›Paper›PMID 40376367›Full record

ArticleCureus2025

Autoimmune Hepatitis (AIH) Related to Drug-Induced Liver Injury (DILI) Due to Atorvastatin.

Jaime Loeza-Suárez, Diana Citlalli García-Luna, Janely Hernández-Mirón, Raúl Ramírez-Marcial, Grissell Alejandra Valero-Gaona

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jaime Loeza-SuárezInternal Medicine, Hospital Juárez de México, México City, MEX.
Diana Citlalli García-LunaInternal Medicine, Hospital Juárez de México, Mexico City, MEX.
Janely Hernández-MirónInternal Medicine, Hospital Juárez de México, Mexico City, MEX.
Raúl Ramírez-MarcialGastroenterology and Hepatology, Hospital Juárez de México, Mexico City, MEX.
Grissell Alejandra Valero-GaonaRheumatology Department, Instituto Mexicano del Seguro Social (IMSS), México City, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-induced liver injury (DILI) is a rare condition characterized by hepatotoxic damage, identified through the elevation of liver function tests associated with a specific drug. Statins are among the medications linked to DILI, although this association is infrequent. Recently, reports and case series have described a relationship between atorvastatin-induced DILI and autoimmune hepatitis (AIH), two conditions not commonly associated. Because there are no established clinical or diagnostic criteria for this overlap, recognition is complex and relies on the clinical course, a timeline of causality, and the exclusion of alternative diagnoses. This report presents the case of a patient in the seventh decade of life who developed atorvastatin-induced DILI, meeting the diagnostic criteria for AIH. We discuss the therapeutic approach and review the relevant literature on this rare association.

Indexed as

atorvastatin-induced autoimmune hepatitisautoimmune hepatitis (aih)drug-induced liver injury (dili)statinstatin-induced hepatitis

Identifiers

PMID40376367
PMCPMC12080954

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.