ReviewBiophysical reviews2025
Mechanics and disease of heart cells/cardiomyocytes explored through atomic force microscopy: present and future.
Review in Biophysical reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- The Emerging Role of Mechanobiology in Connecting Metabolic and Cardiovascular Diseases: From Fundamentals to Future Therapies.Biomedicines · 2026Review
- Mechanical Properties of Endothelial Cells: A Key to Physiology, Drug Testing and Nanostructure Interaction.Cells · 2025Review
- Biophysical reviews (ISSUE 2 2025): LAFeBS, alive, kicking, and growing: the story continues...Biophysical reviews · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
According to the World Health Organization (WHO), cardiovascular diseases are the leading cause of death worldwide. Several diseases have been linked to changes in cellular mechanical properties, including those affecting the heart. Atomic force microscopy (AFM) has proven to be one of the most effective techniques for precisely determining the topography and mechanical properties of adherent living cells. In this review, we provide a short chronological overview of key studies conducted using AFM on cardiac cells or cardiomyocytes with clinical and medical significance. These studies have contributed and continue to enhance our understanding of the pathological processes affecting the heart and clarify the role of cell mechanics in cardiac and cardiovascular diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.