Evidence mapPaperPMID 40377309Full record

ArticleMicrobiology spectrum2025

Synergistic interaction of amphotericin B and betulinic acid against clinically important fungi: evidence from

Bence Rafael, Mónika Homa, Csilla Szebenyi, Csaba Vágvölgyi, Chetna Tyagi, Tamás Papp

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bence RafaelDepartment of Biotechnology and Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
Mónika HomaDepartment of Biotechnology and Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
Csilla SzebenyiDepartment of Biotechnology and Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
Csaba VágvölgyiDepartment of Biotechnology and Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
Chetna TyagiDepartment of Biotechnology and Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
Tamás PappDepartment of Biotechnology and Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.ORCID 0000-0001-8211-5431

Funding

Eötvös Loránd Research Network (ELKH) HUN-REN 2001007Nemzeti Kutatási Fejlesztési és Innovációs Hivatal (NKFI) TKP2021-EGA-28
6 · The paper itself

Abstract

Betulinic acid (BA), in combined application with amphotericin B, shows a synergistic effect against

Indexed as

Amphotericin BAntifungal AgentsFungiTriterpenesAspergillus fumigatusBetulinic AcidDrug SynergismHumansMicrobial Sensitivity TestsMolecular Docking SimulationPentacyclic TriterpenesAmphotericin BAntifungal AgentsBetulinic AcidPentacyclic TriterpenesTriterpenesaspergillosiscandidiasisEagle effectin silico molecular dockingmixed pore formationmucormycosis

Identifiers

PMID40377309
PMCPMC12211039

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.