Evidence map›Paper›PMID 40380100›Full record

ArticleBMC genomics2025

Genetic dissection of hundred-kernel weight through combined genome-wide association study and linkage analysis in tropical maize.

Mengfei Shi, Fuyan Jiang, Ranjan K Shaw, Babar Ijaz, Jiachen Sun, Xingming Fan

Abstract read
In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Mengfei ShiInstitute of Food Crops, Yunnan Academy of Agricultural Sciences, Kunming, 650205, China.
Fuyan JiangInstitute of Food Crops, Yunnan Academy of Agricultural Sciences, Kunming, 650205, China.
Ranjan K ShawInstitute of Food Crops, Yunnan Academy of Agricultural Sciences, Kunming, 650205, China.
Babar IjazInstitute of Food Crops, Yunnan Academy of Agricultural Sciences, Kunming, 650205, China.
Jiachen SunInstitute of Food Crops, Yunnan Academy of Agricultural Sciences, Kunming, 650205, China.
Xingming FanInstitute of Food Crops, Yunnan Academy of Agricultural Sciences, Kunming, 650205, China. xingmingfan@163.com.

Funding

the High-level Scientific and Technological Talents and Innovation Team Program of Yunnan Province 202405AS350030
6 · The paper itself

Abstract

backgroundHundred-kernel weight (HKW) is a crucial determinant of maize yield. Understanding the genetic mechanisms underlying HKW is vital for maize breeding programs aimed at enhancing productivity. This study aimed to explore the genetic basis of HKW in maize using a multi-parent population (MPP), developed by crossing the common male parent Ye107 with five female parents representing a range of kernel sizes and weights. The MPP was evaluated under two distinct environmental conditions (19DH and 19BS).

resultsGenotyping-by-sequencing (GBS) identified 591,483 high-quality single nucleotide polymorphisms (SNPs), which were used for a genome-wide association study (GWAS) and linkage analysis. The GWAS revealed 21 SNPs significantly associated with HKW, with Zm00001d028188, a gene involved in cell wall synthesis, emerging as a key candidate located on chromosome 1. This gene, encodes Galacturonosyltransferase 1 (GAUT1) and overlapped with two identified quantitative trait loci (QTLs): qHKW1-2 and qHKW1-3, which were further validated through linkage analysis.

conclusionsThis study identified critical genetic loci and candidate genes, such as Zm00001d028188, involved in regulating HKW in maize. The findings provide valuable genomic resources for maize breeding, potentially contributing to the development of high-yielding maize varieties through an enhanced understanding of the genetic control of HKW.

Indexed as

Genetic LinkageGenome-Wide Association StudySeedsZea maysChromosome MappingGenome, PlantGenotypePhenotypePlant BreedingPolymorphism, Single NucleotideQuantitative Trait LociGenome-wide association studyHundred-kernel weightMaizeMulti-parent population

Identifiers

PMID40380100
PMCPMC12085011

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.