Evidence map›Paper›PMID 40381076›Full record

ArticleJournal of community health2025

Non-fatal Overdose and Associated Factors Among People Who Use Opioids: Findings From a Cross-sectional Study.

Md Safaet Hossain Sujan, Jeffrey A Wickersham, Antoine Khati, Kiran Paudel, Kamal Gautam, Dominique Liautaud, Haley P Crim, Anushka Thapa, Michael M Copenhaver, Roman Shrestha

Abstract read
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In one paragraph

Article in Journal of community health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Md Safaet Hossain SujanDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, 06269, USA.
Jeffrey A WickershamSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, 135 College St., Suite 323, New Haven, CT, 06510, USA.
Antoine KhatiDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, 06269, USA.
Kiran PaudelDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, 06269, USA.
Kamal GautamDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, 06269, USA.
Dominique LiautaudDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, 06269, USA.
Haley P CrimDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, 06269, USA.
Anushka ThapaSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, 135 College St., Suite 323, New Haven, CT, 06510, USA.
Michael M CopenhaverDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, 06269, USA.
Roman ShresthaDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, 06269, USA. roman.shrestha@uconn.edu.ORCID 0000-0003-4340-3101

Funding

Optimizing HIV Prevention Among Opioid-Dependent PersonsK24DA051344 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI MICHAEL COPENHAVER · 2020 to 2026
$1.3M
Training in MHealth Prevention with MSMK01DA051346 · NIDA · YALE UNIVERSITY · PI SHRESTHA, ROMAN · 2020 to 2024
$862k
NIDA NIH HHS K01 DA051346NIDA NIH HHS K24 DA051344
6 · The paper itself

Abstract

People who use opioids (PWUO) face a higher risk of overdose, often resulting in significant morbidity and mortality within this population. Understanding the factors that contribute to non-fatal overdose among PWUO is essential for developing effective prevention strategies. Thus, the present study aimed to report on the history of and factors associated with non-fatal opioid overdose among PWUO. From April to June 2024, 199 adults with a recent history of opioid use were enrolled in a cross-sectional study to evaluate past experiences of non-fatal overdose. Participants self-reported their socio-demographic characteristics, experiences with overall overdose, history of opioid use, alcohol consumption, and mental health symptoms. Bivariate and multivariate logistic regression analyses were conducted to assess the correlations between the outcome variables. The mean age of participants was 44.2 years (SD = 10.2). Approximately 49.2% of participants had experienced an opioid overdose at some point. Opioid dependence, alcohol use disorder, and depressive symptoms were reported by 83.9%, 65.8%, and 58.3% of participants, respectively. Older participants were less likely to experience an overdose (aOR: 0.9, 95% CI: 0.9-0.9). On the other hand, participants who were opioid-dependent (aOR: 4.4, 95% CI: 1.7-11.7) and those experiencing suicidal ideation (aOR: 1.8, 95% CI: 1.0-3.5) were more likely to have ever experienced an opioid overdose. Our study demonstrated high rates of non-fatal opioid overdose among PWUO. This finding highlights the need for targeted harm reduction interventions and cross-sector collaboration to address opioid dependency and suicidal ideation, aiming to prevent overdoses in this population.

Indexed as

Analgesics, OpioidDrug OverdoseOpioid-Related DisordersAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedRisk FactorsAnalgesics, OpioidFentanylMental healthNon-fatal overdoseOpioid dependentSubstance use

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.