Evidence map›Paper›PMID 40381089›Full record

ReviewCurrent obesity reports2025

The Impact of Different Nutritional Approaches on Body Composition in People Living with Obesity.

Martina Galasso, Ludovica Verde, Luigi Barrea, Silvia Savastano, Annamaria Colao, Gema Frühbeck, Giovanna Muscogiuri

Registry-linked trialAbstract readReview
In one paragraph

Review in Current obesity reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07431593 (Clinical Significance and Prognostic Value of Systemic Immune Inflammation Index and Systemic Inflammation Response Index in Obesity and Associated Metabolic Complications), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07431593 recruitingnot on this mapstarted 2026, after this paper: background citation

Clinical Significance and Prognostic Value of Systemic Immune Inflammation Index and Systemic Inflammation Response Index in Obesity and Associated Metabolic Complications

TypeobservationalSponsorUniversity of RijekaRan2026 to 2027Enrolled200ConditionsOverweight and Obesity, Inflammation, Metabolic SyndromeArmsNutritional counselling
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Martina Galasso *Dipartimento Di Medicina Clinica E Chirurgia, Centro Italiano Per La Cura E Il Benessere del Paziente Con Obesità (C.I.B.O), Università Degli Studi Di Napoli Federico II, Via Sergio Pansini 5, 80131, Naples, Italy.
Ludovica Verde *Department of Public Health, University of Naples Federico II, Via Sergio Pansini 5, 80131, Naples, Italy.
Luigi Barrea *Dipartimento Psicologia E Scienze Della Salute, Università Telematica Pegaso, Centro Direzionale Isola F2, Via Porzio, 80143, Naples, Italy.
Silvia SavastanoDipartimento Di Medicina Clinica E Chirurgia, Centro Italiano Per La Cura E Il Benessere del Paziente Con Obesità (C.I.B.O), Università Degli Studi Di Napoli Federico II, Via Sergio Pansini 5, 80131, Naples, Italy.
Annamaria ColaoDipartimento Di Medicina Clinica E Chirurgia, Centro Italiano Per La Cura E Il Benessere del Paziente Con Obesità (C.I.B.O), Università Degli Studi Di Napoli Federico II, Via Sergio Pansini 5, 80131, Naples, Italy.
Gema FrühbeckMetabolic Research Laboratory, Cancer Center Clínica Universidad de Navarra (CCUN), Avda. Pío XII, 36, 31008, Pamplona, Spain.
Giovanna MuscogiuriDipartimento Di Medicina Clinica E Chirurgia, Centro Italiano Per La Cura E Il Benessere del Paziente Con Obesità (C.I.B.O), Università Degli Studi Di Napoli Federico II, Via Sergio Pansini 5, 80131, Naples, Italy. giovanna.muscogiuri@unina.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis narrative review aimed to provide an overview of the current evidence on the impact of various nutritional strategies on body composition in people living with obesity (PLwO), with particular attention to fat mass (FM), fat-free mass (FFM), and fat distribution. RECENT

findingsObesity is increasingly linked to cardiometabolic complications, yet common diagnostic metrics such as body mass index (BMI) do not capture changes in FM or FFM. Recent studies highlight the variable effects of different dietary interventions on body compartments. High-protein and ketogenic diets are associated with greater preservation of FFM and reductions in visceral adipose tissue (VAT), while the Mediterranean diet shows promise for long-term adherence and improvements in metabolic health. Intermittent fasting and time-restricted eating demonstrate efficacy in FM reduction but present mixed results regarding FFM retention and sustainability. Dietary strategies exert diverse effects on body composition in PLwO, underscoring the importance of tailoring interventions to individual metabolic profiles and health goals. Personalized nutrition approaches that prioritize the preservation of lean mass and reduction of VAT, along with sustainable adherence, are critical for optimizing obesity management beyond weight loss alone.

Indexed as

Body CompositionObesityBody Mass IndexDiet, KetogenicDiet, MediterraneanHumansWeight LossBody compositionNutritional approachesObesityPersonalized nutritionWeight loss maintenance

Identifiers

PMID40381089
PMCPMC12085324

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.