ArticleScientific reports2025
Natural, vaccine-induced immunity and the probability of experiencing SARS-CoV-2 infection in a household cohort in Rio de Janeiro.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Household SARS-CoV-2 transmission during Omicron wave in Chiang Mai, Thailand: a prospective observational study.The Lancet regional health. Southeast Asia · 2026Article
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14 authors.
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Abstract
The impact of COVID-19 vaccines on real-world transmission remains poorly understood and represents a key public health challenge. This study aimed to investigate natural, vaccine-induced immunity and the probability of experiencing SARS-CoV-2 infection in a cohort of families living in Rio de Janeiro. The participants were categorized into immune groups based on recent infection (within the past 9 months) and vaccination status, considering the type of vaccine received, the number of doses, and the strength of their immune response over time. We estimated the transmission probability within clusters using a multivariate model. From May 2020 to June 2023, we enrolled 669 individuals from 182 households; 272 clusters and 288 index cases were identified. Household transmission occurred in 124 (45.6%) clusters. During the pre-VoC period we did not find any factors associated with transmission. In the Gamma/Delta period, previous infections reduced the probability of transmission (OR = 0.088; 95%CI 0.023-0.341), while in the Omicron period, having a healthcare worker in the household (OR = 0.486; 95%CI 0.256-0.921) and hybrid immunity (OR = 0.095; 95%CI 0.010-0.924) decreased the probability of transmission. Our findings provide strong support for the protective effect of regular vaccination against household transmission in a cohort of families exposed to successive SARS-CoV-2 variants.
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