Evidence map›Paper›PMID 40383961›Full record

ArticleIntegrative cancer therapies

Anticancer Effect of Pinostrobin on Human Breast Cancer Cells Through Regulation of Epithelial Mesenchymal Transition.

Pimrapat Jongjang, Sutharinee Likitnukul, Somrudee Reabroi, Supachoke Mangmool, Bodee Nutho, Darawan Pinthong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pimrapat JongjangMahidol University, Bangkok, Thailand.
Sutharinee LikitnukulMahidol University, Bangkok, Thailand.ORCID 0000-0002-2305-9107
Somrudee ReabroiMahidol University, Bangkok, Thailand.
Supachoke MangmoolChiang Mai University, Thailand.
Bodee NuthoMahidol University, Bangkok, Thailand.ORCID 0000-0003-1979-2418
Darawan PinthongMahidol University, Bangkok, Thailand.ORCID 0009-0002-0026-4113

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer, with a high incidence of metastasis and chemoresistance. Epithelial-mesenchymal transition (EMT) is one of the molecular mechanisms that has been linked to the promotion of metastasis, and it can be promoted by several activators including the NF-κB signaling pathway. As a result, targeting EMT may be a potential strategy for treating TNBC. Pinostrobin is one of the important flavonoids found in the rhizome and rootlet of

Indexed as

Antineoplastic AgentsBreast NeoplasmsEpithelial-Mesenchymal TransitionFlavanonesTriple Negative Breast NeoplasmsAntineoplastic Agents, PhytogenicCell Line, TumorCell MovementCell ProliferationCell SurvivalFemaleHumansMCF-7 CellsMolecular Docking SimulationNF-kappa BSignal TransductionAntineoplastic AgentsAntineoplastic Agents, PhytogenicFlavanonesNF-kappa Bpinostrobinepithelial-mesenchymal transitionMCF-7MDA-MB-231pinostrobintriple-negative breast cancer

Identifiers

PMID40383961
PMCPMC12089712

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.