Evidence map›Paper›PMID 40384420›Full record

ReviewMass spectrometry reviews

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real-Time Chemical Analysis.

Xin Luo, Huiling Wang, Xiaolan Hu, Sasho Gligorovski, Xue Li, Pablo Sinues

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Mass spectrometry reviews. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xin LuoCollege of Environment and Climate, Institute of Mass Spectrometry and Atmospheric Environment, Guangdong Provincial Key Laboratory of Speed Capability Research, Jinan University, Guangzhou, China.
Huiling WangCollege of Environment and Climate, Institute of Mass Spectrometry and Atmospheric Environment, Guangdong Provincial Key Laboratory of Speed Capability Research, Jinan University, Guangzhou, China.
Xiaolan HuCollege of Environment and Climate, Institute of Mass Spectrometry and Atmospheric Environment, Guangdong Provincial Key Laboratory of Speed Capability Research, Jinan University, Guangzhou, China.
Sasho GligorovskiDepartment of Environmental Science and Engineering, Guangdong Technion - Israel Institute of Technology, Shantou, China.
Xue LiCollege of Environment and Climate, Institute of Mass Spectrometry and Atmospheric Environment, Guangdong Provincial Key Laboratory of Speed Capability Research, Jinan University, Guangzhou, China.ORCID https://orcid.org/0000-0001-9247-0584
Pablo SinuesUniversity Children's Hospital Basel, Basel, Switzerland.ORCID https://orcid.org/0000-0001-5602-2880

Funding

Financial support for this work was provided to PS by the Fondation Botnar (Switzerland) and the Swiss National Science Foundation (PCEGP3_181300). XL received funding from National Natural Science Foundation of China (No. 22122603), Guangdong Provincial International Science and Technology Cooperation Project (No. 2022A0505050044), Guangdong Major Project of Basic and Applied Basic Research (No. 2023B0303000013) and Research Fund Program of Guangdong Provincial Key Laboratory of Speed Capability Research (2023B1212010008).
6 · The paper itself

Abstract

In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas-phase molecules via secondary ionization. Around 20 years later-coinciding with the ambient mass spectrometry revolution-secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry were revisited and further developed to analyze complex mixtures of gas and aerosol samples in real-time yet with high sensitivity. During the past two decades, these mass spectrometric techniques have been applied across a broad range of applications, such as the detection of illicit drugs, environmental aerosol analysis, and a series of metabolomic studies through the analysis of volatiles emitted from living organisms. This review offers a comprehensive overview of the progress of SESI and EESI applications since their emergence. Finally, we discuss the opportunities, challenges, along with future directions of SESI and EESI techniques.

Indexed as

applicationselectrospray extraction ionizationmass spectrometrysecondary electrospray ionization

Identifiers

PMID40384420
PMCPMC12866386

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.