ArticleFrontiers in pharmacology2025
Honeysuckle extracts as a potential inhibitor of SARS-CoV-2 infection.
Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: In the current era of coronavirus disease 2019 (COVID-19), we were interested in searching for medications other than the currently available antiviral drugs Paxlovid and Molnupiravir that cause minimal side effects and do not harm the human body. Honeysuckle extract (HSE) is a traditional Chinese medicine (TCM) that has been shown to exert antiviral effects in other studies. However, no studies have indicated whether HSE has an inhibitory effect on SARS-CoV-2. Methods: We prepared HSEs from dried honeysuckle flowers. We performed a cell viability assay, median tissue culture infection dose (TCID Results: In this study, post-treatment with HSE resulted in dose-dependent decreases in both the RNA levels and TCID Conclusion: The results suggest that HSEs may have the potential to prevent SARS-CoV-2 infection.
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