ArticleFrontiers in psychiatry2025
Bidirectional association between depression and cognition in Chinese middle-aged and older women: a 10-year longitudinal study.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Adverse Childhood Experiences, Depression and Subjective Cognitive Decline by Gender: A Moderated Mediation Analysis.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026Article
- Association between cognitive leisure activities and symptoms of depression in Chinese middle-aged and older adults: A CHARLS cohort study from 2011 to 2018.Global mental health (Cambridge, England) · 2026Article
- Article
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Authors and funding
2 authors.
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Abstract
Background: Women's health is an important issue worldwide, and as the population is aging, the health of middle-aged and older women is becoming increasingly vital. Although many studies have examined the relationship between cognition and depression, few studies have been conducted specifically with middle-aged and older women. This study used a longitudinal approach to examine the bidirectional relationship between cognition and depression in middle-aged and older women. Methods: The study used three waves (2011, 2015, and 2020) of data from the China Health and Retirement Longitudinal Study (CHARLS), enrolling a total of 4,618 middle-aged and older women aged over 45 years. Participants' general demographic characteristics were analyzed descriptively, and changes in study variables were measured using repeated-measures analysis of variance. Generalized estimating equation (GEE) and cross-lagged models were used to investigate the longitudinal relationship between depression and cognition. Results: The results of the GEE and cross-lagged models revealed that previous cognitive problems lead to future depression and prior depressive conditions affect subsequent cognition. Conclusions: There is a bidirectional relationship between depression and cognition in middle-aged and older women over time. More clinical mechanisms need to be explored in the future.
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