Evidence map›Paper›PMID 40386603›Full record

ArticleJournal of gastrointestinal oncology2025

Anne Santerre, María Del Rosario Huizar-López, Jaime Coronilla-Martínez, Pablo Cesar Ortiz-Lazareno, Josefina Casas-Solís

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of gastrointestinal oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anne SanterreCellular and Molecular Biology Department, University of Guadalajara, Zapopan, Mexico.ORCID https://orcid.org/0000-0003-2460-9630
María Del Rosario Huizar-López *Cellular and Molecular Biology Department, University of Guadalajara, Zapopan, Mexico.ORCID https://orcid.org/0000-0002-0803-9087
Jaime Coronilla-MartínezVeterinary Medicine Department, University of Guadalajara, Zapopan, Mexico.ORCID https://orcid.org/0009-0007-1076-9576
Pablo Cesar Ortiz-LazarenoImmunology Unit, Western Biomedical Research Center, Mexican Social Security Institute, Guadalajara, Mexico.ORCID https://orcid.org/0000-0001-9045-7052
Josefina Casas-Solís *Cellular and Molecular Biology Department, University of Guadalajara, Zapopan, Mexico.ORCID https://orcid.org/0000-0001-7880-7240

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Colitis-associated colon cancer (CAC) is a specific subset of colorectal cancer (CRC) affecting patients with inflammatory bowel diseases (IBDs). Chronic colon inflammation orchestrates immune surveillance or escape and may drive neoplastic initiation and progression. Methods: BALB/c mice (n=7/group) received two doses of AOM (10 mg/kg body weight) followed by three 5-day cycles of 2% DSS. Results: AOM-DSS induced CAC in BALB/c mice, which presented severe colon damage, high cytokine levels, and altered KRAS and APC expression. Conversely, Conclusions: The present experimental work supports the therapeutic potential of

Indexed as

adenomatosis polyposis coli (APC)colitis-associated colon cancer (CAC)cytokinesKristen rat viral sarcoma oncogene homolog (KRAS)Lacticaseibacillus casei 393 (L. casei 393)

Identifiers

PMID40386603
PMCPMC12078812

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.