Evidence map›Paper›PMID 40386616›Full record

ArticleJournal of gastrointestinal oncology2025

Edward Horwell, Charlotte Freer-Smith, Huynh A Hong, Philip Bearn, Simon M Cutting

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of gastrointestinal oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Edward HorwellDepartment of Biomedical Science, The Bourne Laboratory, Royal Holloway University of London, London, UK.ORCID https://orcid.org/0000-0002-6476-9906
Charlotte Freer-SmithFaculty of Life Sciences & Medicine, King's College University of London, London, UK.
Huynh A HongDepartment of Biomedical Science, The Bourne Laboratory, Royal Holloway University of London, London, UK.
Philip BearnDepartment of Colorectal Surgery, Ashford and St Peter's NHS Foundation Trust, Surrey, UK.
Simon M CuttingDepartment of Biomedical Science, The Bourne Laboratory, Royal Holloway University of London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ulcerative colitis (UC) is a chronic inflammatory condition of the colon. There is a direct correlation between the severity and chronicity of colitis and subsequent risk of colitis associated colorectal cancer (CAC). We have recently shown that a strain of Methods: CAC was induced in mice (BALB/c) by the administration of intraperitoneal azoxymethane (AOM) and chronic colitis by multiple cycles of dextran sulphate sodium (DSS). Mice were divided into four groups: (I) a negative control; (II) a positive control; (III) the treatment arm receiving Results: Compared to the positive control, there was a significant reduction in both the severity and chronicity of colitis in the group receiving Conclusions:

Indexed as

azoxymethane/dextran sulphate sodium (AOM/DSS)bacillusColitis associated colorectal cancer (CAC)inflammatory bowel disease (IBD)Toll-like receptors (TLRs)

Identifiers

PMID40386616
PMCPMC12078832

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.