Trial reportPhysiological reports2025
Acute effect of lower-limb peristaltic pulse external pneumatic compression on segmental arterial stiffness in healthy young adults.
Trial report in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
Abstract
Although an acute bout of peristaltic pulse external pneumatic compression (EPC) of the lower extremities can improve vascular function, its effect on arterial stiffness remains unclear. This study aimed to investigate the acute effect of lower-limb peristaltic pulse EPC on segmental arterial stiffness. Nineteen healthy young adults (12 males and 7 females) (age: 20 ± 1 years) were allocated to undergo two experimental trials using a randomized crossover design. EPC treatment delivered at 70-80 mmHg (EPC trial) or non-compressed sham treatment (sham trial) was performed for 30 min. At baseline (Pre) and after the 30-min treatment (Post), arterial stiffness indices, including the heart-brachial pulse wave velocity (PWV) (hbPWV), brachial-ankle PWV (baPWV), heart-ankle PWV (haPWV), and the cardio-ankle vascular index (CAVI) were measured simultaneously. All parameters in the EPC trial exhibited a significant decrease (p < 0.05) at Post compared to Pre, including hbPWV, baPWV, haPWV, and CAVI. However, no such changes were observed in the sham trial. The study findings demonstrate that a single 30-min bout of lower-limb peristaltic pulse EPC can decrease arterial stiffness in healthy young adults. The observed EPC-induced decrease in arterial stiffness in various segments suggests that the beneficial vascular effect could be elicited systemically.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.