Evidence map›Paper›PMID 40388510›Full record

ArticleCirculation2025

Leveraging Transcriptional Readouts as a Platform for Drug Repurposing in Cardiomyopathy.

Ahmed I Mahmoud, Hesham A Sadek

Abstract readEditorialComment
In one paragraph

Article in Circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Ahmed I MahmoudCenter for Cardiovascular and Muscular Diseases, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (A.I.M.).ORCID 0000-0003-1528-7393
Hesham A SadekCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (H.A.S.).ORCID 0000-0002-4745-366X

Funding

Project 3 - Role of Proline Metabolism in Regulation of Mammalian Cardiomyocyte ProliferationP01HL160476 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Hesham Sadek · 2022 to 2026
$13.1M
T-Cell-Mediated Inflammatory Response in Neonatal Heart RegenerationP01HL160488 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI Hesham Sadek · 2023 to 2026
$10.2M
Supply and Demand: Oxygen and Workload Regulate Cardiomyocyte ProliferationR35HL166563 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI Hesham Sadek · 2023 to 2026
$4.1M
Metabolic Reprogramming of the Adult Heart to a Regenerative StateR01HL166256 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Ahmed I Mahmoud · 2023 to 2026
$1.8M
Targeting Metabolism To Stimulate Adult Heart RegenerationR56HL155617 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MAHMOUD, AHMED I · 2021 to 2021
$393k
NHLBI NIH HHS P01 HL160476NHLBI NIH HHS P01 HL160488NHLBI NIH HHS R01 HL166256NHLBI NIH HHS R35 HL166563NHLBI NIH HHS R56 HL155617
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cardiomyopathiesEditorialsgene expression

Identifiers

PMID40388510
PMCPMC12092052

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.