Evidence map›Paper›PMID 40389645›Full record

ArticleScientific reports2025

Transcriptomic profiling of immune modulation induced by vitamin D

Emilia Gospodarska, Ranjini Ghosh Dastidar, Julia Jaroslawska, Maciej Rybiński, Marianna Raczyk, Kornelia Tokarczyk-Malesa, Jerzy Romaszko, Carsten Carlberg

Registry-linked trialAbstract readClinical Trial, Phase I
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06104111 (Investigating the Mechanisms of Epigenetic Memory at the Example of the Responsiveness of Human Immune Cells to Vitamin D), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06104111 phase1unknown statusnot on this map

Investigating the Mechanisms of Epigenetic Memory at the Example of the Responsiveness of Human Immune Cells to Vitamin D

TypeinterventionalSponsorPolish Academy of SciencesRan2023 to 2025Enrolled50ConditionsImmune System Diseases, Infections, Healthy LifestyleArmsVitamin D3
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. 25-Hydroxyvitamin DCommunications medicine · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emilia Gospodarska *Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, ul. Trylińskiego 18, 10-683, Olsztyn, Poland.
Ranjini Ghosh Dastidar *Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, ul. Trylińskiego 18, 10-683, Olsztyn, Poland.
Julia JaroslawskaInstitute of Animal Reproduction and Food Research, Polish Academy of Sciences, ul. Trylińskiego 18, 10-683, Olsztyn, Poland.
Maciej RybińskiInstitute of Animal Reproduction and Food Research, Polish Academy of Sciences, ul. Trylińskiego 18, 10-683, Olsztyn, Poland.
Marianna RaczykInstitute of Animal Reproduction and Food Research, Polish Academy of Sciences, ul. Trylińskiego 18, 10-683, Olsztyn, Poland.
Kornelia Tokarczyk-MalesaDepartment of Family Medicine and Infectious Diseases, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.
Jerzy RomaszkoDepartment of Family Medicine and Infectious Diseases, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.
Carsten CarlbergInstitute of Animal Reproduction and Food Research, Polish Academy of Sciences, ul. Trylińskiego 18, 10-683, Olsztyn, Poland. c.carlberg@pan.olsztyn.pl.

Funding

European Commission 952601Narodowe Centrum Nauki 2023/49/B/NZ9/00402
6 · The paper itself

Abstract

The VitDPAS study (NCT06104111) was designed as a medical experiment to assess the in vivo effects of vitamin D on immune responses. This study enrolled 45 healthy individuals from Olsztyn, Poland, who received a body weight-adjusted bolus dose of vitamin D

Indexed as

CholecalciferolGene Expression ProfilingTranscriptomeAdultCohort StudiesDietary SupplementsFemaleFinlandHumansLeukocytes, MononuclearMaleMiddle AgedSignal TransductionYoung AdultCholecalciferolInflammatory responseTranscriptomeVitamin DVitamin D intervention studiesVitamin D response indexVitamin D target genes

Identifiers

PMID40389645
PMCPMC12089289

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.