Evidence map›Paper›PMID 40390259›Full record

ArticleActa dermato-venereologica2025

Determinants of Quality of Life in Patients with Atopic Dermatitis and Psoriasis: A Multivariate Approach.

Carsten Spitzer, Ines Buchholz, Laura Lübke, Clara Wülfing, Katharina Meier, Georgios Kokolakis, Dennis Niebel, Caroline Mann, Ante Karoglan, Steffen Emmert and 1 more

Abstract read
In one paragraph

Article in Acta dermato-venereologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carsten SpitzerDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center Rostock, Rostock, Germany. carsten.spitzer@med.uni-rostock.de.ORCID 0000-0002-2711-285X
Ines BuchholzEuroQol Group, Rotterdam, The Netherlands.ORCID 0000-0001-9729-6992
Laura LübkeDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center Rostock, Rostock, Germany.ORCID 0009-0009-4217-3958
Clara WülfingDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center Rostock, Rostock, Germany; Clinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany.
Katharina MeierDepartment of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-4687-3195
Georgios KokolakisDepartment of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-8042-7885
Dennis NiebelDepartment of Dermatology, University Hospital Regensburg, Regensburg, Germ.ORCID 0000-0003-2069-0486
Caroline MannDepartment of Dermatology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.ORCID 0000-0001-7044-2216
Ante KaroglanDermatology Practice, Berlin, Germany.ORCID 0000-0002-6100-5927
Steffen EmmertClinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany.ORCID 0000-0001-5630-4204
Alexander ThiemClinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany.ORCID 0000-0001-9504-4281

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Health-related quality of life (HRQoL) is reduced in atopic dermatitis and psoriasis. Several factors impact HRQoL including sociodemographic and skin disease-related characteristics, health behaviours, cardiometabolic comorbidities, and psychological conditions. However, their differential and unique effects on HRQoL are not well studied. In this cross-sectional online survey, adult patients with atopic dermatitis (n = 155) or psoriasis (n = 246) provided data on features of their respective skin diseases, health behaviours, and cardiometabolic comorbidities. Validated self-report measures assessed HRQoL, psychopathology (Patient Health Questionnaire-4), and stress (Perceived Stress Scale). Linear regression analyses were used to determine key predictors of HRQoL. In atopic dermatitis, linear regression analyses revealed that self-rated disease severity (Patient-Oriented Eczema Measure), anxiety, and stress were significant predictors of the Dermatology Life Quality Index (DLQI), explaining 59% of the variance. In psoriasis, disease severity (Psoriasis Symptoms and Signs Diary) and depression significantly predicted DLQI, with an explained variance of 57%. Health behaviours and cardiometabolic comorbidities did not impact DLQI scores. While skin disease severity is the most important determinant of HRQoL, stress and anxiety are important in atopic dermatitis, whereas depression is relevant in psoriasis. These findings hold implications for both clinical practice and research.

Indexed as

Dermatitis, AtopicPsoriasisQuality of LifeAdolescentAdultAgedAnxietyComorbidityCross-Sectional StudiesDepressionFemaleHealth BehaviorHumansLinear ModelsMaleMiddle Aged

Identifiers

PMID40390259
PMCPMC12105536

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.