Evidence map›Paper›PMID 40392269›Full record

ArticleEuropean journal of applied physiology2025

Metabolomic profiles and antioxidant intake in female soccer players: a cross-sectional study.

M M S Gouveia, M B A Nascimento, A C Crispim, E R da Rocha, M P P Santos, E S Bento, T M Aquino, P Balikian, N A Rodrigues, T Ataide-Silva and 2 more

Abstract read
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In one paragraph

Article in European journal of applied physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

M M S GouveiaFaculty of Nutrition, Federal University of Alagoas, Maceió, Brazil.ORCID http://orcid.org/0000-0002-0647-1933
M B A NascimentoFaculty of Nutrition, Federal University of Alagoas, Maceió, Brazil.ORCID http://orcid.org/0009-0007-4480-3103
A C CrispimNucleus of Analysis and Research in Nuclear Magnetic Resonance, NAPRMN, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Macéio, Brazil.ORCID http://orcid.org/0000-0002-4182-2727
E R da RochaNucleus of Analysis and Research in Nuclear Magnetic Resonance, NAPRMN, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Macéio, Brazil.ORCID http://orcid.org/0000-0002-1358-5031
M P P SantosLaboraty of Applied Sports Science, Institute of Physical Education and Sports, Federal University of Alagoas, Macéio, Brazil.ORCID http://orcid.org/0000-0003-2840-865X
E S BentoNucleus of Analysis and Research in Nuclear Magnetic Resonance, NAPRMN, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Macéio, Brazil.
T M AquinoNucleus of Analysis and Research in Nuclear Magnetic Resonance, NAPRMN, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Macéio, Brazil.ORCID http://orcid.org/0000-0001-9138-8466
P BalikianLaboraty of Applied Sports Science, Institute of Physical Education and Sports, Federal University of Alagoas, Macéio, Brazil.
N A RodriguesLaboraty of Applied Sports Science, Institute of Physical Education and Sports, Federal University of Alagoas, Macéio, Brazil.ORCID http://orcid.org/0000-0003-4265-9586
T Ataide-SilvaFaculty of Nutrition, Federal University of Alagoas, Maceió, Brazil.ORCID http://orcid.org/0000-0001-9031-1491
G G de AraujoFaculty of Nutrition, Federal University of Alagoas, Maceió, Brazil.ORCID http://orcid.org/0000-0003-4609-069X
F A B SousaFaculty of Nutrition, Federal University of Alagoas, Maceió, Brazil. filipe.sousa@iefe.ufal.br.ORCID http://orcid.org/0000-0001-8252-725X

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 408972/2021-1Fundação de Amparo à Pesquisa do Estado de Alagoas E60030.0000000161/2022
6 · The paper itself

Abstract

purposeExcessive reactive oxygen species (ROS) production during sports can impair performance and recovery. A diet rich in exogenous antioxidants plays a key role in counteracting oxidative stress, and its complex interactions with various circulating compounds can be explored through metabolomics. With the rising popularity of women's soccer, a deeper understanding of dietary intake and its metabolic interactions in female athletes is needed. The study's aims are to assess the habitual dietary intake of antioxidant micronutrients and their associations with oxidative/antioxidant metabolites in female professional soccer players through NMR-based metabolomics.

methodsThis cross-sectional study included 14 professional female soccer players. Urine samples were collected before and immediately after six games (three per championship) and analyzed by NMR-based metabolomics. Habitual food intake was recorded through 11 food diaries during the preseason. The focus was on vitamins A, C, and E, selenium, zinc, and magnesium. Associations were assessed using Pearson correlations and the DIABLO model.

resultsAmong the antioxidant micronutrients, only vitamin C and selenium met adequate intake levels. The metabolomics analysis identified 41 metabolites, with key markers of oxidative stress-malonic acid, pyruvate, and glycine-showing strong associations with vitamin E, magnesium, selenium, and zinc, particularly before the game.

conclusionThe antioxidant micronutrient intake of most athletes did not meet the recommended levels. Malonic acid showed positive correlations, while glycine had negative correlations with these micronutrients before the game, suggesting a potential link between antioxidant activity at rest and habitual nutrient intake.

Indexed as

AntioxidantsMetabolomeSoccerAdultAthletesCross-Sectional StudiesFemaleHumansMetabolomicsMicronutrientsOxidative StressYoung AdultAntioxidantsMicronutrientsMetabolomicsMicronutrientsNuclear magnetic resonanceOxidative stressSoccer

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.