Evidence map›Paper›PMID 40392387›Full record

ReviewInflammopharmacology2025

Carica papaya in health and disease: a review of its bioactive compounds for treating various disease conditions, including anti-inflammatory and anti-arthritic activities.

Md Khokon Miah Akanda, A H M Nazmul Hasan, Sanzia Mehjabin, G M Masud Parvez, Sabina Yasmin, Md Sayeed Akhtar, Saistha Anjum, Sumel Ashique, Rokeya Sulatana, Mohammad Yousuf Ansari

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Various parts ofFrontiers in molecular biosciences · 2026
    Review
  2. EnhancedDrug delivery · 2025
    Article
  3. The Anti-Inflammatory and Skin Barrier Function Recovery Effects ofInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Md Khokon Miah AkandaDepartment of Pharmacy, University of Asia Pacific, Dhaka, 1205, Bangladesh.
A H M Nazmul HasanDepartment of Pharmacy, University of Asia Pacific, Dhaka, 1205, Bangladesh.
Sanzia MehjabinDepartment of Pharmacy, Varendra University, Rajshahi, 6204, Bangladesh.
G M Masud ParvezDepartment of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, GA, 30602, USA.
Sabina YasminDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.
Md Sayeed AkhtarDepartment of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.
Saistha AnjumDepartment of Pharmacology, Kanak Manjari Institute of Pharmaceutical Sciences (KMIPS), Rourkela, Odisha, 769015, India.
Sumel AshiqueDepartment of Pharmaceutical Technology, Bharat Technology, Uluberia, West Bengal, 711316, India. ashiquesumel007@gmail.com.
Rokeya SulatanaDepartment of Pharmacognosy, Yenepoya Pharmacy College & Research Centre, Yenepoya (Deemed to be University), Mangalore, Karnataka, India.
Mohammad Yousuf AnsariMM College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, 133207, India. yousufniper@gmail.com.ORCID http://orcid.org/0000-0001-6365-7104

Funding

Deanship of Scientific Research, King Khalid University RGP. 2/405/46.
6 · The paper itself

Abstract

Plants and their compounds are extensively utilized in various industries, including pharmacy, medicine, food, and cosmetics, making the papaya (Carica papaya) fruit tree economically vital in tropical and subtropical regions. This review provides detailed information on the traditional uses, nutritional content, phytochemistry, and pharmacological activity of C. papaya. The authors conducted a comprehensive search using databases like Scopus, PubMed, Scilit, and Google Scholar to gather relevant articles on this title. Papaya extract is commonly used to treat various health issues, including inflammation and pain, hypertension, diabetes, dermatitis, asthma, and stomach problems due to its rich chemical compositions of flavonoids, steroids, sterol, and β-sitosterol. C. papaya extracts exhibit numerous properties anti-inflammatory, anti-ulcer, anti-arthritic, analgesic, anti-fertility, anti-cancer, anti-bacterial, antiviral, wound-healing, etc. in both laboratory and animal studies. C. papaya may contain new active compounds for treating various ailments, but toxicity, efficacy, and clinical trials are needed before its therapeutic use.

Indexed as

Anti-Inflammatory AgentsCaricaPhytochemicalsPlant ExtractsAnimalsHumansInflammationPhytotherapyAnti-Inflammatory AgentsPhytochemicalsPlant ExtractsCarica papayaChemical constituentsNutritional valuePharmacological activityToxicological studiesTraditional use

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.