Evidence map›Paper›PMID 40394381›Full record

ArticleScientific reports2025

Oxyresveratrol enhances hair regeneration in human dermal papilla cell and androgenetic alopecia mouse model.

Hung Gia Tran, Aussavashai Shuayprom, Alisa Ruchusatsawat, Kornvalee Meesilpavikkai, Virgil A S H Dalm, Kriangsak Ruchusatsawat, Jongkonnee Wongpiyabovorn

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hung Gia TranCenter of Excellence in Immune-Mediated Diseases, Division of Immunology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Aussavashai ShuaypromRegional Medical Sciences Center 3 Nakhonsawan, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand.
Alisa RuchusatsawatEngineering Science Classroom, King Mongkut's University of Technology, Thonburi, Bangkok, Thailand.
Kornvalee MeesilpavikkaiDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
Virgil A S H DalmDepartment of Immunology, Laboratory Medical Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Kriangsak RuchusatsawatMedical Sciences Technical Office, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand.
Jongkonnee WongpiyabovornCenter of Excellence in Immune-Mediated Diseases, Division of Immunology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand. jongkonnee.w@chula.ac.th.

Funding

Ratchadapiseksompotch Fund, Faculty of Medicine, Chulalongkorn University GA65/74Thailand Science, Research, and Innovation Fund Chulalongkorn University BCG_FF_68_068_3000_011
6 · The paper itself

Abstract

Alopecia, or hair loss, is a common dermatological condition caused by multiple factors. Oxyresveratrol (ORV), a compound derived from the heartwood of Artocarpus lakoocha, is recognized for its potent antioxidant properties, with recent studies highlighting its anti-inflammatory effect across various cell types. This study aims to explore the therapeutic potential of ORV in treating alopecia. We evaluated the effects of ORV on Human Follicle Dermal Papilla Cells (HFDPCs) and an androgenetic alopecia (AGA) mouse model. Oxidative stress in HFDPCs was induced using hydrogen peroxide (H

Indexed as

AlopeciaHairHair FolliclePlant ExtractsRegenerationStilbenesAnimalsAntioxidantsCell ProliferationDermisDisease Models, AnimalHumansHydrogen PeroxideMaleMiceMice, Inbred C57BLAntioxidantsHydrogen PeroxidePlant Extractspuag-haadReactive Oxygen SpeciesStilbenesAlopeciaAnti-inflammationDihydrotestosteroneHair regenerationOxyresveratrol

Identifiers

PMID40394381
PMCPMC12092586

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.