Evidence map›Paper›PMID 40396045›Full record

ReviewAutophagy reports2022

Evaluating Autophagy in Preimplantation Embryos.

Zuleika C L Leung, Hailey L M Hunter, Basim Abu Rafea, Andrew J Watson, Dean H Betts

Abstract readReview
In one paragraph

Review in Autophagy reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Autophagy-related gene and protein expressions during blastocyst development.Journal of assisted reproduction and genetics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zuleika C L LeungDepartment of Obstetrics and Gynaecology.
Hailey L M HunterDepartment of Physiology and Pharmacology, The University of Western Ontario, London Ontario, Canada, N6A 5C1.
Basim Abu RafeaDepartment of Obstetrics and Gynaecology.
Andrew J WatsonDepartment of Obstetrics and Gynaecology.
Dean H BettsDepartment of Obstetrics and Gynaecology.ORCID https://orcid.org/0000-0002-5528-9142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy is an essential cellular degradation pathway in the mammalian preimplantation embryo. In this review, the process of autophagy is outlined and its function pertaining to preimplantation embryos is discussed. The current methods of measuring autophagy in preimplantation embryos are also summarized, with highlights of advances and challenges that one may encounter when examining preimplantation embryo autophagy. This article identifies the techniques, assays, and available models that are viable but infrequently used in the context of examining autophagy in preimplantation embryos. We aim to bring attention to alternative assays that could contribute to future analysis of autophagic pathways in preimplantation embryos.

Indexed as

ATGAutophagyembryonic stem cellsLC3preimplantation embryo

Identifiers

PMID40396045
PMCPMC11864692

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.