Evidence map›Paper›PMID 40396967›Full record

ArticleTurk patoloji dergisi2025

Comprehensive Evaluation of the Utility of Cell Block Use in ThinPrep Liquid-Based Cervical Specimens.

Yasemin Akca, Evren Uzun, Suna Erkilic

Abstract readEvaluation Study
In one paragraph

Article in Turk patoloji dergisi, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yasemin AkcaDepartment of Pathology, Gaziantep University, Faculty of Medicine, GAZIANTEP, TÜRKİYE.
Evren UzunDepartment of Pathology, Gaziantep University, Faculty of Medicine, GAZIANTEP, TÜRKİYE.
Suna ErkilicDepartment of Pathology, Gaziantep University, Faculty of Medicine, GAZIANTEP, TÜRKİYE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe Papanicolaou (PAP) smear remains the cornerstone of early detection and prevention in cervical cancer screening, Today, liquid-based cytology (LBC) techniques are more widely used for this purpose. ThinPrep is one of the most effective of these methods. In this study, we aimed to investigate the contributions of the cell block method when using ThinPrep liquid-based cervical samples. MATERIAL AND

methodsWe retrospectively reviewed a total of 453 cases in which we applied cell block to assist in correct diagnosis in terms of four criteria we determined from ThinPrep LBC samples accepted to our department between 2020 and 2023. We investigated the benefits of cell block according to the four criteria we defined in these cases; these criteria were adequacy, determination of cellular origin based on atrophy, and correct diagnosis of squamous cell lesions and glandular cell lesions. Cell blocks were re-evaluated by 3 experienced pathologists, and the results were analyzed.

resultsThe cell block method contributed significantly to the adequacy in 97 of the 136 samples. It contributed to understanding the cellular origin and correct diagnosis of atrophic background in 113 of the 165 samples. It also contributed to the correct diagnosis of squamous cell lesions in 26 of the 107 samples and glandular cell lesions in 40 of the 45 samples. Overall, it was detected to be useful in 272 out of 453 cases.

conclusionThe cell-block method represents powerful contributions for each parameter, especially if it is used selectively, particularly in evaluating glandular cell lesions and atrophic background. Additionally, it facilitates ancillary testing in the field of cervical cancer screening and management.

Indexed as

Cervix UteriPapanicolaou TestUterine Cervical NeoplasmsVaginal SmearsAdultAgedEarly Detection of CancerFemaleHumansMiddle AgedRetrospective Studies

Identifiers

PMID40396967
PMCPMC12527554

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.