Evidence map›Paper›PMID 40397181›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2026

Sex differences in event-related potentials and their clinical predictive value in first-episode antipsychotic-naïve schizophrenia.

Qin Qin, Chenghao Lu, Shaobing Li, Nannan Liu, Yanzhe Li, Tongxin Li, Yeqing Dong, Xinxu Wang, Shen Li, Jie Li and 1 more

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In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qin Qin *National Clinical Research Center for Mental Disorders & National Center for Mental Disorders, Capital Medical University , Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Beijing, China.
Chenghao Lu *Institute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, No. 13, Liulin Road, Hexi District, Tianjin, 300222, China.
Shaobing LiInstitute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, No. 13, Liulin Road, Hexi District, Tianjin, 300222, China.
Nannan LiuInstitute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, No. 13, Liulin Road, Hexi District, Tianjin, 300222, China.
Yanzhe LiInstitute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, No. 13, Liulin Road, Hexi District, Tianjin, 300222, China.
Tongxin LiInstitute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, No. 13, Liulin Road, Hexi District, Tianjin, 300222, China.
Yeqing DongInstitute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, No. 13, Liulin Road, Hexi District, Tianjin, 300222, China.
Xinxu WangInstitute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, No. 13, Liulin Road, Hexi District, Tianjin, 300222, China.
Shen LiInstitute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, No. 13, Liulin Road, Hexi District, Tianjin, 300222, China. lishen@tmu.edu.cn.ORCID http://orcid.org/0000-0002-7157-7945
Jie LiInstitute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, No. 13, Liulin Road, Hexi District, Tianjin, 300222, China. jieli@tjmhc.com.
Xiang Yang ZhangCAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, 16 Lincui Road, Chaoyang District, Beijing, 100101, China. zhangxy@psych.ac.cn.

Funding

National Key Research and Development Program of China 2023YFF1203700National Natural Science Foundation of China 82371512Tianjin Health Research Project TJWJ2024MS037
6 · The paper itself

Abstract

This study explored sex differences in cognitive impairments in first-episode antipsychotic-naive schizophrenia (FEAN-SZ) patients using event-related potentials. A total of 321 FEAN-SZ patients and 146 healthy controls (HCs) were enrolled to compare sex differences in the P300 (P3) components elicited by the auditory Oddball paradigm. The Positive and Negative Syndrome Scale (PANSS), Hamilton Depression Scale (HAMD), and Hamilton Anxiety Scale (HAMA) were used to assess the clinical symptoms. We also examined sex differences in the relationship between P3 components and clinical symptoms. Compared to HCs, FEAN-SZ patients showed reduced P3 amplitude and prolonged latency (all p

Indexed as

Cognitive DysfunctionEvent-Related Potentials, P300Evoked PotentialsSchizophreniaSex CharacteristicsAdolescentAdultElectroencephalographyFemaleHumansMalePsychiatric Status Rating ScalesYoung AdultCognitive impairmentEvent-related potentialFirst-episode antipsychotic-naïveSchizophreniaSex differences

Identifiers

PMID40397181

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.