Evidence mapPaperPMID 40399392Full record

ArticleScientific reports2025

Treatment satisfaction and associated factors among patients with rheumatoid arthritis in North West Ethiopia.

Tigabu Eskeziya Zerihun, Abaynesh Fentahun Bekalu, Abel Temeche Kassaw, Desalegn Addis Mussie, Woretaw Sisay Zewdu, Fisseha Nigussie Dagnew, Getachew Yitayew Tarekegn, Samuel Berihun Dagnew, Tilaye Arega Moges, Belayneh Yitayew Wallie and 3 more

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Tigabu Eskeziya ZerihunDepartment of Clinical Pharmacy, Pharmacy Education and Clinical Services Directorate, College of Health Sciences, Debre Tabor University, P.O. Box 272, Debre Tabor, Ethiopia. eskeziatigabu@gmail.com.
Abaynesh Fentahun BekaluDepartment of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Abel Temeche KassawDepartment of Clinical Pharmacy, Pharmacy Education and Clinical Services Directorate, College of Health Sciences, Debre Tabor University, P.O. Box 272, Debre Tabor, Ethiopia.
Desalegn Addis MussieDepartment of Clinical Pharmacy, Pharmacy Education and Clinical Services Directorate, College of Health Sciences, Debre Tabor University, P.O. Box 272, Debre Tabor, Ethiopia.
Woretaw Sisay ZewduDepartment of Pharmacology and Toxicology, Pharmacy Education and Clinical Services Directorate, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Fisseha Nigussie DagnewDepartment of Clinical Pharmacy, Pharmacy Education and Clinical Services Directorate, College of Health Sciences, Debre Tabor University, P.O. Box 272, Debre Tabor, Ethiopia.
Getachew Yitayew TarekegnDepartment of Clinical Pharmacy, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Samuel Berihun DagnewDepartment of Clinical Pharmacy, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Tilaye Arega MogesDepartment of Clinical Pharmacy, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Belayneh Yitayew WallieDepartment of Pharmacy, College of Medicine and Health Science, Wachamo University, Hosanna, Ethiopia.
Eliyas Addisu TayeDepartment of Health Informatics, School of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Teferi Bihonegn MeleseDepartment of Clinical Pharmacy, Pharmacy Education and Clinical Services Directorate, College of Health Sciences, Debre Tabor University, P.O. Box 272, Debre Tabor, Ethiopia.
Abebech Tewabe GelayeDepartment of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis is a chronic autoimmune inflammatory joint condition that progressively becomes devastating. Patient satisfaction with treatment is a predictor of medication adherence. Not only this, but it also affects the correct use of medication. Findings in this area are insufficient and contradictory. Therefore, this study aimed to assess treatment satisfaction and associated factors among patients with rheumatoid arthritis in northwest Ethiopia in 2024. A multi-center cross-sectional study was conducted among 393 rheumatoid arthritis patients attending the rheumatoid follow-up clinic of five comprehensive specialized hospitals in northwest Ethiopia from June 21 to September 20, 2024. A systematic random sampling technique was used to collect data. The Treatment Satisfaction with Medicines Questionnaire was used to determine treatment satisfaction. Face-to-face interviews with respondents from selected hospitals were used to gather data. Multiple linear regression was done to identify associated factors. Statistical significance was declared as p-value < 0.05. 393 participants were included in the study. The mean age was 52.28 (SD, 13.43). Around 75.6% were female, and 56.5% were married. Around 42.7% of patients had moderate disease activity, and 53.9% had comorbidities. The overall scores of treatment satisfaction were 52.8 (SD, 10.5). Treatment satisfaction was negatively associated with not taking therapeutic education (β =  - 0.14, 95% CI (- 6.12, - 1.54), p = 0.001), high disease activity (β =  - 0.31, 95% CI (- 12.64, - 0.45), p = 0.035), unavailability of medication (β =  - 0.13, 95% CI (- 6.22, - 1.09), p = 0.005), ≥ 5-year duration of disease (β =  - 0.16, 95% CI (- 7.01, - 1.45), p = 0.003). The present study revealed that overall treatment satisfaction was good. Duration of disease, disease activity, unavailability of medication and therapeutic education were factors affecting treatment satisfaction. Therefore, it is essential to prioritize therapeutic education and medication availability for patients with extended disease durations and high disease activity to improve treatment satisfaction.

Indexed as

Antirheumatic AgentsArthritis, RheumatoidPatient SatisfactionAdultAgedCross-Sectional StudiesEthiopiaFemaleHumansMaleMiddle AgedSurveys and QuestionnairesAntirheumatic AgentsEthiopiaRheumatoid arthritisTreatment satisfaction

Identifiers

PMID40399392
PMCPMC12095517

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.