Evidence map›Paper›PMID 40399514›Full record

ArticleSurgery today2025

Impact of body composition on the development of pancreatic fistula after pancreaticoduodenectomy.

Ryosuke Fukushima, Norifumi Harimoto, Kenichiro Araki, Kouki Hoshino, Kei Hagiwara, Shunsuke Kawai, Norihiro Ishii, Mariko Tsukagoshi, Takamichi Igarashi, Norio Kubo and 1 more

Abstract read
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Article in Surgery today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ryosuke FukushimaDivision of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi, Japan.
Norifumi HarimotoDivision of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi, Japan.
Kenichiro ArakiDivision of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi, Japan. karaki@gunma-u.ac.jp.
Kouki HoshinoDivision of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi, Japan.
Kei HagiwaraDivision of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi, Japan.
Shunsuke KawaiDivision of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi, Japan.
Norihiro IshiiDivision of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi, Japan.
Mariko TsukagoshiDivision of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi, Japan.
Takamichi IgarashiDivision of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi, Japan.
Norio KuboDivision of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi, Japan.
Ken ShirabeDivision of Hepatobiliary and Pancreatic Surgery, Department of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePostoperative pancreatic fistula (POPF) is a clinically relevant complication of pancreaticoduodenectomy (PD). We focused on the association between body composition and the development of POPF. This study aimed to identify which aspects of body composition have the strongest impact.

methodsWe retrospectively reviewed the records of 218 patients who underwent PD from 2016 to 2023. We assessed the following aspects of body composition in terms of their predictive value for POPF: body mass index, skeletal muscle index, visceral fat area, subcutaneous fat area, intramuscular adipose tissue content (IMAC), and depth of the pancreas on preoperative computed tomography.

resultsA multivariate analysis revealed that a high visceral fat area, high IMAC, and more deeply positioned pancreas were independent risk factors for POPF. Although the visceral fat-associated aspects of body composition were statistically significant, sarcopenia-associated factors were not. Moreover, in patients with a normal pancreas, a high IMAC and deeper pancreas were independent risk factors for POPF.

conclusionsHigh IMAC and deeper pancreas were significant risk factors for POPF regardless of pancreatic stump texture. Preoperative assessment of body composition factors could be important for predicting POPF after PD and for identifying high-risk patients.

Indexed as

Body CompositionPancreatic FistulaPancreaticoduodenectomyPostoperative ComplicationsAdultAgedAged, 80 and overBody Mass IndexFemaleHumansIntra-Abdominal FatMaleMiddle AgedPancreasRetrospective StudiesRisk FactorsBody compositionDepth of pancreasIntramuscular adipose tissue contentPancreatic fistulaPancreaticoduodenectomy

Identifiers

PMID40399514

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.