ArticleNature2025
Clonal tracing with somatic epimutations reveals dynamics of blood ageing.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed.
- Computational approaches for multimodal lineage tracing.Nature reviews. Genetics · 2026Review
- Article
- A single-cell lens into the co-evolution of genotypes and phenotypes in cancer.Nature reviews. Cancer · 2026Review
- Single-cell DNA methylation analysis uncovers epigenetic pathways in the transformation of MDS to AML.Leukemia · 2026Article
- Embracing non-linearity in human ageing.Nature reviews. Genetics · 2026Review
- Spatio-DARLIN enables robust and efficient in situ lineage tracing in mice at single-cell resolution.Nature methods · 2026Article
- Lineage tracing from cellular heritage to disease destiny.Nature genetics · 2026Review
- Improving lymphopoiesis in aged bone marrow.Current opinion in hematology · 2026Review
- Transcriptional heterogeneity predicts and enables clonal selection in ageing haematopoiesis.Research square · 2026Article
- Conception-calibrated male pediatric tumor mitotic clocks.Communications biology · 2026Article
- Architectural fragility of gene regulatory networks underlies hematopoietic stem cell aging.bioRxiv : the preprint server for biology · 2026Article
- Charting single-cell lineages with synthetic and natural barcodes.Nature reviews. Genetics · 2026Review
- Aging mechanisms and rejuvenation strategies for hematopoietic stem cells.Genome biology · 2026Review
- MiTo: tracing the phenotypic evolution of somatic cell lineages via mitochondrial single-cell multi-omics.Nature communications · 2026Article
- BCR-ABL1 Drives Transcriptional Reprogramming of Chronic Myeloid Leukemia Cells for Immune Evasion Through C/EBPβ.MedComm · 2026Article
- Redefining cellular reprogramming with advanced genomic technologies.Nature reviews. Genetics · 2026Review
- Hematopoietic stem cell-independent and -dependent hematopoiesis: new insights and lineage-tracing methods.Experimental hematology · 2026Review
- DNA methylation meets lineage tracing: History, recent progress, and future directions.Quantitative biology (Beijing, China) · 2026Article
- Modeling mitochondrial inheritance enables high-precision single-cell lineage tracing in humans.bioRxiv : the preprint server for biology · 2026Article
- Blood-based epigenetic instability linked to human aging and disease.Nature communications · 2026Article
Corrections and comments
- Update of
Authors and funding
25 authors.
Michael Scherer *Computational Biology and Health Genomics, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID 0000-0001-7990-6179
Indranil Singh *Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.ORCID 0000-0002-2143-986X
Martina Maria Braun *Computational Biology and Health Genomics, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID 0009-0004-1274-6317
Chelsea Szu-Tu *Computational Biology and Health Genomics, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona, Spain.
Pedro Sanchez SanchezInstitute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.ORCID 0000-0002-4846-1813
Dominik LindenhoferGenome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.ORCID 0000-0001-8838-7163
Niels Asger JakobsenMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-5776-5085
Verena KörberMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.ORCID 0009-0005-3888-2648
Michael KardorffDepartment of Medicine, Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.ORCID 0009-0008-9720-6166
Lena NitschBerlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.
Pauline KautzBerlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-9658-1676
Julia RühleComputational Biology and Health Genomics, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID 0000-0002-1479-3633
Agostina BianchiComputational Biology and Health Genomics, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona, Spain.
Luca CozzutoComputational Biology and Health Genomics, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona, Spain.
Robert FrömelComputational Biology and Health Genomics, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID 0000-0002-0438-8677
Sergi Beneyto-CalabuigComputational Biology and Health Genomics, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID 0000-0003-3773-8239
Caleb LareauComputational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0003-4179-4807
Ansuman T SatpathyDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0002-5167-537X
Renée BeekmanComputational Biology and Health Genomics, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID 0000-0001-7081-7874
Lars M SteinmetzGenome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Simon RaffelDepartment of Medicine, Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.
Leif S LudwigBerlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-2916-2164
Paresh VyasMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.ORCID 0000-0003-3931-0914
Alejo Rodriguez-FraticelliInstitute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. alejo.rodriguez-fraticelli@irbbarcelona.org.ORCID 0000-0002-4017-8714
Lars VeltenComputational Biology and Health Genomics, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona, Spain. lars.velten@crg.eu.ORCID 0000-0002-1233-5874
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4MCharting somatic evolution via single-cell multiomicsR00HG012579 · NHGRI · SLOAN-KETTERING INST CAN RESEARCH · PI LAREAU, CALEB ANDREW · 2023 to 2025
$747kmechanisms of in situ functional stem cell heterogeneity in native and transplantation hematopoiesisK99HL146983 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI RODRIGUEZ FRATICELLI, ALEJO EZEQUIEL · 2019 to 2020
$336kEuropean Hematology Association, by the Fundación Asociación Española Contra el CáncerNCI NIH HHS P30 CA008748NHGRI NIH HHS R00 HG012579NHLBI NIH HHS K99 HL146983
Abstract
Current approaches used to track stem cell clones through differentiation require genetic engineering
Indexed as
AgingCell LineageClone CellsEpigenesis, GeneticHematopoiesisMutationAdultAgedAnimalsCell DifferentiationCellular SenescenceCpG IslandsDNA MethylationFemaleHematopoietic Stem CellsHumans
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What Socratic holds
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LicenceCC BY-NC-ND
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.