Evidence map›Paper›PMID 40401953›Full record

ArticleMicrobiology spectrum2025

Coupled dopamine and insulin signaling mediated transgenerational and multigenerational inheritance of adaptive traits in

Bynedi Seshadhri Chinna Mounish, Balasubramanian Chellammal Muthubharathi, Thirumugam Gowripriya, Koilmani Emmanuvel Rajan, Krishnaswamy Balamurugan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bynedi Seshadhri Chinna MounishDepartment of Biotechnology, Alagappa University, Karaikudi, Tamil Nadu, India.ORCID 0009-0008-8539-215X
Balasubramanian Chellammal MuthubharathiDepartment of Biotechnology, Alagappa University, Karaikudi, Tamil Nadu, India.
Thirumugam GowripriyaDepartment of Biotechnology, Alagappa University, Karaikudi, Tamil Nadu, India.
Koilmani Emmanuvel RajanBehavioural Neuroscience Laboratory, Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.
Krishnaswamy BalamuruganDepartment of Biotechnology, Alagappa University, Karaikudi, Tamil Nadu, India.ORCID 0000-0001-9316-8141

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nervous system's ability to perceive and learn about the environment can help organisms evolve and acquire traits, potentially generating adaptive responses. However, its potential to produce heritable modulations is a scientific lacuna, which is under-explored. Here, with the help of

Indexed as

Caenorhabditis elegansDopamineInsulinSalmonella typhiAdaptation, PhysiologicalAnimalsCaenorhabditis elegans ProteinsForkhead Transcription FactorsReceptor, InsulinSignal TransductionCaenorhabditis elegans Proteinsdaf-16 protein, C elegansDAF-2 protein, C elegansDopamineForkhead Transcription FactorsInsulinReceptor, InsulinDopamine signalingMultigenerational adaptationsNeuronal plasticityTransgenerational inheritance

Identifiers

PMID40401953
PMCPMC12211078

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.