Evidence mapPaperPMID 40402408Full record

ReviewMolecular neurobiology2025

The Role of Fatty Acid Binding Protein 7 in Neurological Diseases.

Yingxi Chen, Jiarui Liu, Yurou He, Yang Lü, Weihua Yu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yingxi ChenInstitute of Neuroscience, Chongqing Medical University, No. 1 Yixuayuan Road, Yu Zhong District, Chongqing, 400016, China.
Jiarui LiuDepartment of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Yurou HeInstitute of Neuroscience, Chongqing Medical University, No. 1 Yixuayuan Road, Yu Zhong District, Chongqing, 400016, China.
Yang LüDepartment of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Weihua YuInstitute of Neuroscience, Chongqing Medical University, No. 1 Yixuayuan Road, Yu Zhong District, Chongqing, 400016, China. yuweihua@cqmu.edu.cn.

Funding

Chongqing Medical University Graduate Top talent training program BJRC202303Key Project of Science and Technology Research Program of Chongqing Municipal Education Commission KJZD-K202200405Natural Science Foundation of Chongqing, China Grant No. 2024NSCQ-LZX020
6 · The paper itself

Abstract

Fatty acid binding protein 7 (FABP7) is a pivotal cytoplasmic protein involved in the transport and metabolism of fatty acids, with critical functions in the nervous system. This review highlights recent advances in understanding the role and mechanisms of FABP7 in neurological diseases. It begins with an overview of FABP7's distribution and expression in the nervous system, emphasizing its involvement in essential biological processes such as lipid metabolism, energy regulation, synaptic transmission, cell growth, and neuroinflammation. This review also explores FABP7's associations with major neurological disorders, including Alzheimer's disease (AD), Parkinson's disease (PD), schizophrenia, and depression, shedding light on its dual roles in neuroprotection and neurodegeneration. These findings position FABP7 as a promising target for novel therapeutic strategies. By unraveling its precise mechanisms and contributions to both neural health and disease, future research on FABP7 has the potential to revolutionize treatments for neurological disorders, offering innovative directions for therapeutic development.

Indexed as

Fatty Acid-Binding Protein 7Nervous System DiseasesAnimalsHumansLipid MetabolismFatty Acid-Binding Protein 7Energy homeostasisFatty acid binding protein 7Lipid metabolismNeuroinflammationNeurological disordersSynaptic transmission

Identifiers

PMID40402408

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.